Evidence map›Paper›PMID 27722140›Full record

ArticleJournal of cancer prevention2016

The Immunomodulatory Activity of Mori folium, the Leaf of

Da Hye Kwon, Ji Min Cheon, Eun-Ok Choi, Jin Woo Jeong, Ki Won Lee, Ki Young Kim, Sung Goo Kim, Suhkmann Kim, Su Hyun Hong, Cheol Park and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of cancer prevention, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Morus alba: a comprehensive phytochemical and pharmacological review.Naunyn-Schmiedeberg's archives of pharmacology · 2023
    Review
  3. Antioxidant and Immune Stimulating Effects ofAntioxidants (Basel, Switzerland) · 2022
    Article
  4. Article
  5. Review
  6. Pharmacological Activities forFoods (Basel, Switzerland) · 2021
    Review
  7. Article
  8. Review
  9. The Immunomodulatory Activities ofOpen access Macedonian journal of medical sciences · 2019
    Article
  10. Identification of Anti-Melanogenesis Constituents fromMolecules (Basel, Switzerland) · 2018
    Article
  11. [Sanggenon C induces apoptosis of prostate cancer PC3 cells by activating caspase 3 and caspase 9 pathways].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Da Hye KwonAnti-Aging Research Center, Busan, Korea.
Ji Min CheonDepartment of Food and Nutrition, Dongeui University, Busan, Korea.
Eun-Ok ChoiAnti-Aging Research Center, Busan, Korea; Department of Biochemistry, Dongeui University College of Korean Medicine, Busan, Korea.
Jin Woo JeongAnti-Aging Research Center, Busan, Korea; Department of Biochemistry, Dongeui University College of Korean Medicine, Busan, Korea.
Ki Won LeeBio-Port Korea Inc., MarineBio-industry Development Center, Busan, Korea.
Ki Young KimBio-Port Korea Inc., MarineBio-industry Development Center, Busan, Korea.
Sung Goo KimBio-Port Korea Inc., MarineBio-industry Development Center, Busan, Korea.
Suhkmann KimDepartment of Chemistry, Pusan National University, Busan, Korea.
Su Hyun HongDepartment of Biochemistry, Dongeui University College of Korean Medicine, Busan, Korea.
Cheol ParkDepartment of Molecular Biology, Dongeui University, Busan, Korea.
Hye-Jin HwangDepartment of Food and Nutrition, Dongeui University, Busan, Korea.
Yung Hyun ChoiAnti-Aging Research Center, Busan, Korea; Department of Biochemistry, Dongeui University College of Korean Medicine, Busan, Korea.
Dong-Eui University · KRMarine Biodiversity Institute of Korea · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImmunoregulatory elements have emerged as useful immunotherapeutic agents against cancer. In traditional medicine, Mori folium, the leaf of

methodsRAW264.7 cells were treated with WEMF for 24 hours and cell viability was detected by an MTT method. Nitric oxide (NO) levels in the culture supernatants were assayed using Griess reagent. The productions of prostaglandin E

resultsWEMF significantly stimulated the production of NO and PGE

conclusionsWEMF has the potential to modulate the immune function by regulating immunological parameters. Further studies are needed to identify the active compounds and to support the use of WEMF as an immune stimulant.

Indexed as

Immune responseMacrophagesMori foliumPhagocytosis

Identifiers

PMID27722140
PMCPMC5051588
OpenAlexW2527745873

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.