Evidence map›Paper›PMID 27722113›Full record

ArticleInternational journal of critical illness and injury science

Bone marrow hematopoietic stem cells behavior with or without growth factors in trauma hemorrhagic shock.

Manoj Kumar, Sanjeev Bhoi, Sujata Mohanty, Vineet Kumar Kamal, D N Rao, Pravas Mishra, Sagar Galwankar

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of critical illness and injury science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Manoj KumarDepartment of Emergency Medicine, Jai Prakash Narayan Apex Trauma Centre, All India Institute of Medical Sciences, New Delhi, India.
Sanjeev BhoiDepartment of Emergency Medicine, Jai Prakash Narayan Apex Trauma Centre, All India Institute of Medical Sciences, New Delhi, India.
Sujata MohantyDepartment of Stem Cell Facility, All India Institute of Medical Sciences, New Delhi, India.
Vineet Kumar KamalDepartment of Biostatistics, All India Institute of Medical Sciences, New Delhi, India.
D N RaoDepartment of Biochemistry, All India Institute of Medical Sciences, New Delhi, India.
Pravas MishraDepartment of Haematology, All India Institute of Medical Sciences, New Delhi, India.
Sagar GalwankarDepartment of Emergency Medicine, University of Florida, Florida, USA.
All India Institute of Medical Sciences · INUniversity of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHemorrhagic shock (HS) is the major leading cause of death after trauma. Up to 50% of early deaths are due to massive hemorrhage. Excessive release of pro-inflammatory cytokine and hypercatecholamine induces hematopoietic progenitor cells (HPCs) apoptosis, leading to multiorgan failure and death. However, still, result remains elusive for hematopoietic stem cells (HSCs) behavior in trauma HS (T/HS).

objectivesTherefore, our aim was to evaluate the METHODOLOGY: Bone marrow (BM) aspirates (

resultsBM HSCs growth significantly suppressed in T/HS when compared with control group (

conclusionSuppressed HPCs may be reactivated by addition of erythropoietin, GM-CSF, IL-3 alone and with combination in T/HS.

Indexed as

Erythropoietingranulocyte monocyte/macrophage-colony-stimulating factorhematopoietic progenitor cellsinterleukin-3 trauma-hemorrhagic shock

Identifiers

PMID27722113
PMCPMC5051054
OpenAlexW2518809264

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.