ArticleBone research2016
A multiscale 3D finite element analysis of fluid/solute transport in mechanically loaded bone.
Article in Bone research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 57 citations in OpenAlex.
- A 50-year perspective on the use and potential of artiodactyl calcanei in bone adaptation studies.Biological reviews of the Cambridge Philosophical Society · 2026Review
- Bone Evaluation with Micro Finite Element Analysis in Animal Models.Tomography (Ann Arbor, Mich.) · 2025Review
- Predicting cortical bone resorption in the mouse tibia under disuse conditions caused by transient muscle paralysis.Scientific reports · 2025Article
- Toward a clear relationship between mechanical signals and bone adaptation.Mechanobiology in medicine · 2025Review
- Numerical study of interstitial fluid flow behavior in osteons under dynamic loading.BMC musculoskeletal disorders · 2025Article
- Mechanical deformations of bone generate interstitial fluid flow at nanoscale velocities around osteocytes.Frontiers in bioengineering and biotechnology · 2025Article
- Using Finite Element Modeling in Bone Mechanoadaptation.Current osteoporosis reports · 2023Review
- Article
- The role of inhibition of osteocyte apoptosis in mediating orthodontic tooth movement and periodontal remodeling: a pilot study.Progress in orthodontics · 2021Article
- Article
- Numerical analysis of the flow field in the lacunar-canalicular system under different magnitudes of gravity.Medical & biological engineering & computing · 2020Article
- Control of Bone Matrix Properties by Osteocytes.Frontiers in endocrinology · 2020Review
- Study on the biomechanical responses of the loaded bone in macroscale and mesoscale by multiscale poroelastic FE analysis.Biomedical engineering online · 2019Article
- Finite Element Modelling Simulated Meniscus Translocation and Deformation during Locomotion of the Equine Stifle.Animals : an open access journal from MDPI · 2019Article
- Static Preload Inhibits Loading-Induced Bone Formation.JBMR plus · 2019Article
- Solute Transport in the Bone Lacunar-Canalicular System (LCS).Current osteoporosis reports · 2018Review
- Microstructural changes associated with osteoporosis negatively affect loading-induced fluid flow around osteocytes in cortical bone.Journal of biomechanics · 2018Article
- [Research advances of fluid bio-mechanics in bone].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The transport of fluid, nutrients, and signaling molecules in the bone lacunar-canalicular system (LCS) is critical for osteocyte survival and function. We have applied the fluorescence recovery after photobleaching (FRAP) approach to quantify load-induced fluid and solute transport in the LCS
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.