Evidence map›Paper›PMID 27721985›Full record

ArticleNPJ science of learning2016

The differential role of cortical protein synthesis in taste memory formation and persistence.

David Levitan, Shunit Gal-Ben-Ari, Christopher Heise, Tali Rosenberg, Alina Elkobi, Sharon Inberg, Carlo Sala, Kobi Rosenblum

Open access · goldAbstract read
In one paragraph

Article in NPJ science of learning, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Deletion ofeLife · 2020
    Article
  5. Taste Processing: Insights from Animal Models.Molecules (Basel, Switzerland) · 2020
    Review
  6. Activity of Insula to Basolateral Amygdala Projecting Neurons is Necessary and Sufficient for Taste Valence Representation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019
    Article
  7. Article
  8. Article
  9. The Insula and Taste Learning.Frontiers in molecular neuroscience · 2017
    Review
  10. Visualizing Local Protein Synthesis and Its Modulation by FMRP and Visual Experience.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016
    Article
  11. Memory Retrieval Has a Dynamic Influence on the Maintenance Mechanisms That Are Sensitive to ζ-Inhibitory Peptide (ZIP).The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

David LevitanSagol Department of Neurobiology, Center for Gene Manipulation in the Brain, University of Haifa, Mt Carmel, Haifa, Israel.
Shunit Gal-Ben-AriSagol Department of Neurobiology, Center for Gene Manipulation in the Brain, University of Haifa, Mt Carmel, Haifa, Israel.
Christopher HeiseConsiglio Nazionale delle Ricerche Neuroscience Institute and Department of Biotechnology and Translational Medicine, University of Milano, Milan, Italy.
Tali RosenbergSagol Department of Neurobiology, Center for Gene Manipulation in the Brain, University of Haifa, Mt Carmel, Haifa, Israel.
Alina ElkobiSagol Department of Neurobiology, Center for Gene Manipulation in the Brain, University of Haifa, Mt Carmel, Haifa, Israel.
Sharon InbergSagol Department of Neurobiology, Center for Gene Manipulation in the Brain, University of Haifa, Mt Carmel, Haifa, Israel.
Carlo SalaConsiglio Nazionale delle Ricerche Neuroscience Institute and Department of Biotechnology and Translational Medicine, University of Milano, Milan, Italy.
Kobi RosenblumSagol Department of Neurobiology, Center for Gene Manipulation in the Brain, University of Haifa, Mt Carmel, Haifa, Israel.
University of Haifa · ILNational Research Council · ITUniversity of Milan · IT

Funding

Italy TelethonTelethon GGP13187
6 · The paper itself

Abstract

The current dogma suggests that the formation of long-term memory (LTM) is dependent on protein synthesis but persistence of the memory trace is not. However, many of the studies examining the effect of protein synthesis inhibitors (PSIs) on LTM persistence were performed in the hippocampus, which is known to have a time-dependent role in memory storage, rather than the cortex, which is considered to be the main structure to store long-term memories. Here we studied the effect of PSIs on LTM formation and persistence in male Wistar Hola (

Identifiers

PMID27721985
PMCPMC5053367
OpenAlexW2345647599

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.