Evidence map›Paper›PMID 27721920›Full record

ArticleWorld journal of hepatology2016

Ohio solid organ transplantation consortium criteria for liver transplantation in patients with alcoholic liver disease.

Kaveh Hajifathalian, Annette Humberson, Mohamad A Hanouneh, David S Barnes, Zubin Arora, Nizar N Zein, Bijan Eghtesad, Dympna Kelly, Ibrahim A Hanouneh

Abstract read
In one paragraph

Article in World journal of hepatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
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  7. Review
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kaveh HajifathalianKaveh Hajifathalian, Mohamad A Hanouneh, Department of Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, United States.
Annette HumbersonKaveh Hajifathalian, Mohamad A Hanouneh, Department of Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, United States.
Mohamad A HanounehKaveh Hajifathalian, Mohamad A Hanouneh, Department of Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, United States.
David S BarnesKaveh Hajifathalian, Mohamad A Hanouneh, Department of Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, United States.
Zubin AroraKaveh Hajifathalian, Mohamad A Hanouneh, Department of Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, United States.
Nizar N ZeinKaveh Hajifathalian, Mohamad A Hanouneh, Department of Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, United States.
Bijan EghtesadKaveh Hajifathalian, Mohamad A Hanouneh, Department of Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, United States.
Dympna KellyKaveh Hajifathalian, Mohamad A Hanouneh, Department of Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, United States.
Ibrahim A HanounehKaveh Hajifathalian, Mohamad A Hanouneh, Department of Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate risk of recidivism on a case-by-case basis.

methodsFrom our center's liver transplant program, we selected patients with alcoholic liver disease who were listed for transplant based on Ohio Solid Organ Transplantation Consortium (OSOTC) exception criteria. They were considered to have either a low or medium risk of recidivism, and had at least one or three or more months of abstinence, respectively. They were matched based on gender, age, and Model for End-Stage Liver Disease (MELD) score to controls with alcohol-induced cirrhosis from Organ Procurement and Transplant Network data.

resultsThirty six patients with alcoholic liver disease were approved for listing based on OSOTC exception criteria and were matched to 72 controls. Nineteen patients (53%) with a median [Inter-quartile range (IQR)] MELD score of 24 (13) received transplant and were followed for a median of 3.4 years. They were matched to 38 controls with a median (IQR) MELD score of 25 (9). At one and five years, cumulative survival rates (± standard error) were 90% ± 7% and 92% ± 5% and 73% ± 12% and 77% ± 8% in patients and controls, respectively (Log-rank test,

conclusionCompared to traditional criteria for assessment of risk of recidivism, a careful selection process with more flexibility to evaluate eligibility on a case-by-case basis can lead to similar survival rates after transplantation.

Indexed as

Alcoholic liver cirrhosisAlcohol-induced disordersLiver transplantationMortalitySurvival

Identifiers

PMID27721920
PMCPMC5037328

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.