ArticleTherapeutic advances in musculoskeletal disease2016
Best performing definition of accelerated knee osteoarthritis: data from the Osteoarthritis Initiative.
Article in Therapeutic advances in musculoskeletal disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A meta-analysis and a functional study support the influence of mtDNA variant m.16519C on the risk of rapid progression of knee osteoarthritis.Annals of the rheumatic diseases · 2023Pooled it
- Examining Timeliness of Total Knee Replacement Among Patients with Knee Osteoarthritis in the U.S.: Results from the OAI and MOST Longitudinal Cohorts.The Journal of bone and joint surgery. American volume · 2020Pooled it
- Reliability of the CPAK classification assessed on long-leg X-rays in patients undergoing total knee arthroplasty.Arthroplasty (London, England) · 2026Article
- Accelerated knee osteoarthritis: a case description and literature analysis.Quantitative imaging in medicine and surgery · 2025Article
- Identifying trajectories of joint space width loss among previously injured knees: Data from the Osteoarthritis Initiative.PloS one · 2025Article
- Radiomic features of the medial meniscus predicts incident destabilizing meniscal tears: Data from the osteoarthritis initiative.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2024Article
- Meniscal degeneration is prognostic of destabilzing meniscal tear and accelerated knee osteoarthritis: Data from the Osteoarthritis Initiative.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2023Article
- Debate: Intra-articular steroid injections for osteoarthritis - harmful or helpful?Osteoarthritis imaging · 2023Article
- Sarcopenia and Sarcopenic Obesity and Osteoarthritis: A Discussion among Muscles, Fat, Bones, and Aging.Life (Basel, Switzerland) · 2023Review
- Comparative effectiveness of early initiation of oral nonsteroidal anti-inflammatory drug and oral acetaminophen therapies on the time to knee replacement in patients with knee osteoarthritis in Japan.BMC musculoskeletal disorders · 2023Article
- Article
- The combination of an inflammatory peripheral blood gene expression and imaging biomarkers enhance prediction of radiographic progression in knee osteoarthritis.Arthritis research & therapy · 2020Article
- Patient-specific reference values for objective physical function tests: data from the Osteoarthritis Initiative.Clinical rheumatology · 2020Observational
- Risk factors and the natural history of accelerated knee osteoarthritis: a narrative review.BMC musculoskeletal disorders · 2020Review
- Composite quantitative knee structure metrics predict the development of accelerated knee osteoarthritis: data from the osteoarthritis initiative.BMC musculoskeletal disorders · 2020Article
- The incidence and characteristics of accelerated knee osteoarthritis among women: the Chingford cohort.BMC musculoskeletal disorders · 2020Article
- Longitudinal MRI structural findings observed in accelerated knee osteoarthritis: data from the Osteoarthritis Initiative.Skeletal radiology · 2019Observational
- Role of Magnetic Resonance Imaging in Classifying Individuals Who Will Develop Accelerated Radiographic Knee Osteoarthritis.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2019Observational
- Adults With Incident Accelerated Knee Osteoarthritis Are More Likely to Use Pharmacological Treatment Options and Receive Arthroscopic Knee Surgery: Data From the Osteoarthritis Initiative.ACR open rheumatology · 2019Article
- Accelerated Knee Osteoarthritis Is Characterized by Destabilizing Meniscal Tears and Preradiographic Structural Disease Burden.Arthritis & rheumatology (Hoboken, N.J.) · 2019Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundWe evaluated agreement among several definitions of accelerated knee osteoarthritis (AKOA) and construct validity by comparing their individual associations with injury, age, obesity, and knee pain.
methodsWe selected knees from the Osteoarthritis Initiative that had no radiographic knee osteoarthritis [Kellgren-Lawrence (KL) 0 or 1] at baseline and had high-quality quantitative medial joint space width (JSW) measures on two or more consecutive visits (
resultsOver 4 years the incidence rate of AKOA was 0.4%, 0.8%, 15.5%, 22.1%, 12.4%, and 7.2% based on the stringent JSW (averaged and consistent), lenient JSW (averaged and consistent), lenient KL-based definition, and comprehensive KL-based definition. All but one knee that met the stringent JSW definition also met the comprehensive KL-based definition. There was fair substantial agreement between the lenient JSW (averaged), lenient KL-based, and comprehensive KL-based definitions. A comprehensive KL-based definition led to larger effect sizes for injury, age, body mass index, and average pain over 4 years.
conclusionsA comprehensive KL-based definition of AKOA may be ideal because it represents a broader definition of joint deterioration compared with those focused on just joint space or osteophytes alone.
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