Evidence map›Paper›PMID 27721669›Full record

ArticleReports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology

Asymptomatic internal carotid artery occlusion after gamma knife radiosurgery for pituitary adenoma: Report of two cases and review of the literature.

Giorgio Spatola, Laura Frosio, Marco Losa, Antonella Del Vecchio, Martina Piloni, Pietro Mortini

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Giorgio SpatolaDepartment of Neurosurgery and Stereotactic Radiosurgery, Division of Neuroscience, IRCCS Ospedale San Raffaele, 20132 Milan, Italy.
Laura FrosioDepartment of Endocrinology, IRCCS Ospedale San Raffaele, 20132 Milan, Italy.
Marco LosaDepartment of Neurosurgery and Stereotactic Radiosurgery, Division of Neuroscience, IRCCS Ospedale San Raffaele, 20132 Milan, Italy; Department of Endocrinology, IRCCS Ospedale San Raffaele, 20132 Milan, Italy.
Antonella Del VecchioDepartment of Medical Physics, IRCCS Ospedale San Raffaele, 20132 Milan, Italy.
Martina PiloniDepartment of Neurosurgery and Stereotactic Radiosurgery, Division of Neuroscience, IRCCS Ospedale San Raffaele, 20132 Milan, Italy.
Pietro MortiniDepartment of Neurosurgery and Stereotactic Radiosurgery, Division of Neuroscience, IRCCS Ospedale San Raffaele, 20132 Milan, Italy.
IRCCS Ospedale San Raffaele · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGamma knife radiosurgery is an effective and safe treatment modality in the management of pituitary adenomas. Internal carotid occlusion is a rare but possible complication of Gamma Knife Radiosurgery for lesions within the cavernous sinus.

aimTo stress the importance of considering the Internal carotid artery as an organ at risk in cavernous sinus invading adenomas and reduce the dose delivered to this structure whenever possible. CASE DESCRIPTION: We report two cases of asymptomatic occlusion of the intracavernous segment of the internal carotid artery seven years after treatment in acromegalic patients. After trans-sphenoidal surgery, residual tumour was treated with gamma knife radiosurgery. The maximal doses to the affected artery were higher than 40 Gy and the 90% isodose was close to the arterial wall.

conclusionEvery effort should be done to minimize the radiation dose to the internal carotid artery. If not possible, "hot spots" exceeding the 90% isodose close to this vessel should be avoided.

Indexed as

Gamma knife radiosurgeryGrowth hormoneInternal carotid artery occlusionPituitary adenoma

Identifiers

PMID27721669
PMCPMC5045960
OpenAlexW2526128299

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.