ArticleJournal of oral and maxillofacial pathology : JOMFP
A relationship between CD4 count and oral manifestations of human immunodeficiency virus-infected patients on highly active antiretroviral therapy in urban population.
Article in Journal of oral and maxillofacial pathology : JOMFP. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed, 18 citations in OpenAlex.
- Otorhinolaryngological Manifestations among People Living with HIV/AIDS in Dar es Salaam, Tanzania: a Cross-Sectional Study.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Oral hyperpigmentation as an adverse effect of highly active antiretroviral therapy in HIV patients: A systematic review and pooled prevalence.Journal of clinical and experimental dentistry · 2023Review
- Influence of oral biofilm index, caries experience, and laboratory markers of disease progression on the oral carriage of Candida in HIV-infected and non-infected children: a cross-sectional study.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022Article
- CD4 cells count as a prognostic marker in HIV patients with comparative analysis of various studies in Asia Pacific region.Journal of family medicine and primary care · 2020Article
- Oral manifestations, salivary flow rates and Candida species in Thai HIV-infected patients.Journal of clinical and experimental dentistry · 2019Article
- Importance of various oral manifestations regardless of CD4 cell count in HIV/AIDS patients.Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2018Article
- Determine Relationship Between Xerostomia and Quality of Life of HIV Person's Living in Prison.Journal of International Society of Preventive & Community DentistryArticle
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6 authors at 2 institutions in 1 country.
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Abstract
introductionHuman immunodeficiency virus (HIV) infection gradually destroys the body's immune system, which makes it harder for the body to fight infections. HIV infection causes a quantitative and qualitative depletion of CD4 lymphocyte count, which increases the risk of opportunistic infections. Thus, CD4 count is one of the key factors in determining both the urgency of highly active antiretroviral therapy (HAART) initiation and the need of prophylaxis for opportunistic infections.
aimThis study aims to evaluate the prevalence and variations in the oral manifestations of HIV/acquired immune deficiency syndrome patients on HAART therapy in urban population and their association with CD4 count. MATERIALS AND
methodsA study was conducted by screening eighty patients who were HIV positive in an urban location. Both adult and pediatric patients were screened for oral manifestations and simultaneously CD4 count was also evaluated. Patients with HIV infection for variable time period who are under HAART were considered. STATISTICAL ANALYSIS: Measures of central tendency were used to analyse the data.
resultsHIV infection destroys the immune system of an individual, making the patient susceptible to various infections and malignancies. With the advent of antiretroviral therapy, the scenario has changed drastically. We have observed that patients with CD4 counts between 164 and 1286 show relatively few oral manifestations. Long-term HAART therapy causes pigmentation, xerostomia and angular cheilitis but is taken up quite well by the patients.
conclusionIn this study, eighty patients with HAART from urban population showed very minimal oral findings because of good accessibility for treatment and awareness about HIV infections. The patients who were on long-standing HAART treatment also showed minimal oral manifestation such as pigmentation and xerostomia. Hence, we conclude that recognition, significance and treatment of these lesions in patients with HIV infection do not require elaborate setup and can be treated with basic primary health care.
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