Evidence map›Paper›PMID 27721578›Full record

ArticleCurrent directions in psychological science2016

The amygdala and prioritization of declarative memories.

Joseph R Manns, David I Bass

Registry-linked trialAbstract read
In one paragraph

Article in Current directions in psychological science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05065450 (Mechanisms of Amygdala-Mediated Memory Enhancement in Humans), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05065450 narecruitingnot on this mapstarted 2021, after this paper: background citation

Mechanisms of Amygdala-Mediated Memory Enhancement in Humans

TypeinterventionalSponsorWashington University School of MedicineRan2021 to 2027Enrolled90ConditionsBrain Diseases, Epilepsy, Memory Disorders, Traumatic Brain InjuryArmsIntracranial Stimulation
3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Direct electrical stimulation of the amygdala enhances declarative memory in humans.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Trial
  2. Article
  3. Novelty, Ecological Relevance, and Sexual Receptivity Modulate Neuronal Interactions between the Amygdala and Hippocampus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  4. Article
  5. Article
  6. Exploring individual differences in amygdala-mediated memory modulation.Cognitive, affective & behavioral neuroscience · 2025
    Article
  7. Article
  8. Article
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  14. Article
  15. Article
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Joseph R MannsEmory University.
David I BassEmory University.

Funding

Amygdala-mediated enhancement of the hippocampal memory systemR01MH100318 · NIMH · EMORY UNIVERSITY · PI MANNS, JOSEPH R · 2015 to 2019
$1.9M
Amygdala Mediated Enhancement of Object Recognition Memory in the HippocampusF30MH095491 · NIMH · EMORY UNIVERSITY · PI BASS, DAVID I. · 2011 to 2014
$138k
NIMH NIH HHS F30 MH095491NIMH NIH HHS R01 MH100318United States NIMH
6 · The paper itself

Abstract

The present review highlights results from recent studies that delivered brief electrical stimulation to the basolateral complex of the amygdala in rats to reveal its capacity to prioritize declarative memories on a moment-to-moment basis even after the moment has passed. The results indicate that this memory enhancement depends on the hippocampus and elicits intrahippocampal gamma synchrony that possibly corresponds with sharpened hippocampal spike-timing dependent plasticity. These recent findings are discussed in relation to past studies of emotional memory in rodents and humans.

Indexed as

amygdalaconsolidationemotionmemorystimulation

Identifiers

PMID27721578
PMCPMC5049500

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.