Evidence map›Paper›PMID 27721543›Full record

ArticleIndian journal of pharmacology

Anxiolytic, antidepressant, and antistress activities of the aqueous extract of

Gayaprasad Upadhyay, Sarvesh Khoshla, Ramoji Kosuru, Sanjay Singh

Open access · greenAbstract read
In one paragraph

Article in Indian journal of pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Gayaprasad UpadhyayDepartment of Pharmaceutics, Indian Institute of Technology, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Sarvesh KhoshlaDepartment of Pharmaceutics, Indian Institute of Technology, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Ramoji KosuruDepartment of Pharmaceutics, Indian Institute of Technology, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Sanjay SinghDepartment of Pharmaceutics, Indian Institute of Technology, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Banaras Hindu University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe current study was designed to explore anxiolytic, antidepressant, and antistress actions of MATERIALS AND

methodsBehavioral procedures of anxiety, depression, and stress were assessed in rats. CT (100, 200, and 400 mg/kg) was given once a daily for 7 days via oral route and the efficacy was matched by those elicited by lorazepam (1 mg/kg, p.o.), imipramine (10 mg/kg, p.o.), and

resultsOne-way analysis of variance followed by Newman-Keuls multiple comparison test was employed to analyze the results.

conclusionThe study shows that among the different CT doses, CT at 400 mg/kg possesses significant anxiolytic, antidepressant, and anti-stress effects and has therapeutic beneficial for the management of psychological ailments.

Indexed as

CinnamomumAnimalsAnti-Anxiety AgentsAntidepressive AgentsAnxietyBehavior, AnimalBlood GlucoseCholesterolCorticosteroneDepressionExploratory BehaviorFemaleHindlimb SuspensionImipramineInterpersonal RelationsLorazepamAnti-Anxiety AgentsAntidepressive AgentsBlood GlucoseCholesterolCorticosteroneImipramineLorazepamPlant ExtractsTriglyceridesAntidepressantantistressanxiolyticCinnamomum tamalaulcer indexWithania somnifera

Identifiers

PMID27721543
PMCPMC5051251
OpenAlexW2521098379

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.