Evidence map›Paper›PMID 27721326›Full record

ArticlePharmaceuticals (Basel, Switzerland)2011

Novo, S. et al. Aliskiren: Just a New Drug for Few Selected Patients or an Innovative Molecule Predestinated to Replace Arbs and Ace-Inhibitors? Pharmaceuticals 2009, 2, 118-124.

Salvatore Novo, Giovanni Fazio, Elena Raccuglia, Antonino Mignano, Giuseppina Novo

Open access · goldAbstract readPublished Erratum
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Salvatore NovoDepartment of Internal Medicine and Cardiovascular Diseases, University Hospital "Paolo Giaccone", University of Palermo, Italy. novosav@unipa.it.
Giovanni FazioDepartment of Internal Medicine and Cardiovascular Diseases, University Hospital "Paolo Giaccone", University of Palermo, Italy.
Elena RaccugliaDepartment of Internal Medicine and Cardiovascular Diseases, University Hospital "Paolo Giaccone", University of Palermo, Italy.
Antonino MignanoDepartment of Internal Medicine and Cardiovascular Diseases, University Hospital "Paolo Giaccone", University of Palermo, Italy.
Giuseppina NovoDepartment of Internal Medicine and Cardiovascular Diseases, University Hospital "Paolo Giaccone", University of Palermo, Italy.
Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo · ITUniversity of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the published version "Paladini et al. reported that aliskiren 300 mg provided a sustained BP-lowering effect beyond the 24-h dosing interval, with a significantly smaller loss of BP-lowering effect in the 24-48 h period after dose than irbesartan 300 mg or ramipril 10 mg [25]". Paladini et al. should be Palatini et al., and the cited reference number should be [10], not [25].. In the sentence, "Early data suggest a role for aliskiren in preventing end-organ damage but, considering the ONTARGET results with an ACE-I-ARB combination, outcome studies are needed before the use of aliskiren can be recommended in combination with other RAS inhibitors [18-30]" one more citation number was added [5], so the revised sentence is "Early data suggest a role for aliskiren in preventing end-organ damage but, considering the ONTARGET results with an ACE-I-ARB combination, outcome studies are needed before the use of aliskiren can be recommended in combination with other RAS inhibitors [5,18-30]". [...].

Identifiers

PMID27721326
PMCPMC4060125
OpenAlexW2126925840

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.