ArticleClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2016
Effects of cerebellar theta-burst stimulation on arm and neck movement kinematics in patients with focal dystonia.
Article in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06775145 (Therapeutic Effect of Neuromodulation on Anxiety Disorders by High-Definition Transcranial Electrical Stimulation), which is not on this map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Therapeutic Effect of Neuromodulation on Anxiety Disorders by High-Definition Transcranial Electrical Stimulation
Who cites it
33 citing papers in PubMed, 63 citations in OpenAlex.
- Differential effects of propranolol on head and upper limb tremor in patients with essential tremor and dystonia.Journal of neurology · 2018Trial
- Cerebellar rhythms: mechanisms, functions and translational opportunities.Nature reviews. Neuroscience · 2026Review
- Focal Task-Specific Dystonia Beyond M1: Network Adaptations and a Causal-Architecture Taxonomy of Dystonia.Brain sciences · 2026Article
- Versatility of Transcranial Magnetic Stimulation: A Review of Diagnostic and Therapeutic Applications.Brain sciences · 2026Review
- Corticospinal Excitability After Continuous and Intermittent Theta Burst Stimulation Applied on the Lateral Cerebellum: A Study on Healthy Individuals.Noro psikiyatri arsivi · 2026Article
- Subtle bradykinesia features are easier to identify and more prevalent than questionable dystonia in essential tremor.Journal of neural transmission (Vienna, Austria : 1996) · 2025Article
- Research progress in spasmodic torticollis rehabilitation treatment.World journal of clinical cases · 2024Review
- Beyond Pallidal or Subthalamic Deep Brain Stimulation to Treat Dystonia.Tremor and other hyperkinetic movements (New York, N.Y.) · 2024Review
- Applications of Transcranial Magnetic Stimulation for Understanding and Treating Dystonia.Advances in neurobiology · 2023Review
- Consensus Paper: Novel Directions and Next Steps of Non-invasive Brain Stimulation of the Cerebellum in Health and Disease.Cerebellum (London, England) · 2022Article
- A Brief History of Cerebellar Neurostimulation.Cerebellum (London, England) · 2022Review
- Functional abnormalities in the cerebello-thalamic pathways in a mouse model of DYT25 dystonia.eLife · 2022Article
- Effects of non-invasive brain stimulation in dystonia: a systematic review and meta-analysis.Therapeutic advances in neurological disorders · 2022Article
- Cerebellar transcranial current stimulation - An intraindividual comparison of different techniques.Frontiers in neuroscience · 2022Article
- Past, Present, and Future of Deep Brain Stimulation: Hardware, Software, Imaging, Physiology and Novel Approaches.Frontiers in neurology · 2022Review
- New modalities and directions for dystonia care.Journal of neural transmission (Vienna, Austria : 1996) · 2021Review
- Transcranial Magnetic Stimulation in Tremor Syndromes: Pathophysiologic Insights and Therapeutic Role.Frontiers in neurology · 2021Review
- Parietal Cortex Connectivity as a Marker of Shift in Spatial Attention Following Continuous Theta Burst Stimulation.Frontiers in human neuroscience · 2021Article
- Using Probabilistic Movement Primitives in Analyzing Human Motion Differences Under Transcranial Current Stimulation.Frontiers in robotics and AI · 2021Article
- Influence of theta-burst transcranial magnetic stimulation over the dorsolateral prefrontal cortex on emotion processing in healthy volunteers.Cognitive, affective & behavioral neuroscience · 2020Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
objectiveTo investigate the cerebellar inhibitory influence on the primary motor cortex in patients with focal dystonia using a cerebellar continuous theta-burst stimulation protocol (cTBS) and to evaluate any relationship with movement abnormalities.
methodsThirteen patients with focal hand dystonia, 13 patients with cervical dystonia and 13 healthy subjects underwent two sessions: (i) cTBS over the cerebellar hemisphere (real cTBS) and (ii) cTBS over the neck muscles (sham cTBS). The effects of cerebellar cTBS were quantified as excitability changes in the contralateral primary motor cortex, as well as possible changes in arm and neck movements in patients.
resultsReal cerebellar cTBS reduced the excitability in the contralateral primary motor cortex in healthy subjects and in patients with cervical dystonia, though not in patients with focal hand dystonia. There was no correlation between changes in primary motor cortex excitability and arm and neck movement kinematics in patients. There were no changes in clinical scores or in kinematic measures, after either real or sham cerebellar cTBS in patients.
conclusionsThe reduced cerebellar inhibitory modulation of primary motor cortex excitability in focal dystonia may be related to the body areas affected by dystonia as opposed to being a widespread pathophysiological abnormality. SIGNIFICANCE: The present study yields information on the differential role played by the cerebellum in the pathophysiology of different focal dystonias.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.