Evidence map›Paper›PMID 27720918›Full record

ArticleNeurotoxicology2017

Methylmercury induces an initial increase in GABA-evoked currents in Xenopus oocytes expressing α

Tidao Tsai, Yukun Yuan, Ravindra K Hajela, Shuan W Philips, William D Atchison

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurotoxicology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Intestinal microbiota protects against methylmercury-induced neurotoxicity.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tidao TsaiDepartment of Pharmacology and Toxicology, Michigan State University, East Lansing, MI 48824-1317, USA.
Yukun YuanDepartment of Pharmacology and Toxicology, Michigan State University, East Lansing, MI 48824-1317, USA.
Ravindra K HajelaDepartment of Pharmacology and Toxicology, Michigan State University, East Lansing, MI 48824-1317, USA.
Shuan W PhilipsDepartment of Pharmacology and Toxicology, Michigan State University, East Lansing, MI 48824-1317, USA.
William D AtchisonDepartment of Pharmacology and Toxicology, Michigan State University, East Lansing, MI 48824-1317, USA. Electronic address: atchiso1@msu.edu.
Michigan State University · US

Funding

NEUROTOXIC MECHANISMS OF METHYLMERCURY POISONINGR01ES003299 · NIEHS · MICHIGAN STATE UNIVERSITY · PI ATCHISON, WILLIAM D · 1985 to 2012
$5.5M
Environmental Metals, Excitotoxicity and ALSR01ES024064 · NIEHS · MICHIGAN STATE UNIVERSITY · PI ATCHISON, WILLIAM D · 2015 to 2019
$2.4M
Cerebellar GABA-A as Targets of mercury NeurotoxicityR01ES011662 · NIEHS · MICHIGAN STATE UNIVERSITY · PI ATCHISON, WILLIAM D · 2002 to 2005
$1.7M
NIEHS NIH HHS R01 ES003299NIEHS NIH HHS R01 ES011662NIEHS NIH HHS R01 ES024064
6 · The paper itself

Abstract

Early onset effects of methylmercury (MeHg) on recombinant α

Indexed as

AnimalsAnti-Inflammatory Agents, Non-SteroidalBicucullineGABA-A Receptor Antagonistsgamma-Aminobutyric AcidMethylmercury CompoundsNiflumic AcidOocytesProtein SubunitsReceptors, GABA-AXenopus laevisAnti-Inflammatory Agents, Non-SteroidalBicucullineGABA-A Receptor Antagonistsgamma-Aminobutyric Acidmethylmercuric chlorideMethylmercury CompoundsNiflumic AcidProtein SubunitsReceptors, GABA-AGABA(A) receptorHeterologous expressionMethylmercuryα(1) and α(6) subunit

Identifiers

PMID27720918
PMCPMC5726768
OpenAlexW2530750005

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.