Evidence map›Paper›PMID 27720388›Full record

ReviewBiological psychiatry2017

Insights About Striatal Circuit Function and Schizophrenia From a Mouse Model of Dopamine D

Eleanor H Simpson, Christoph Kellendonk

Open access · greenAbstract readReview
In one paragraph

Review in Biological psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Animal Models of Relevance to the Schizophrenia Prodrome.Biological psychiatry global open science · 2023
    Review
  11. Article
  12. Review
  13. The role of orphan receptor GPR139 in neuropsychiatric behavior.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Article
  14. Dorsal striatal dopamine induces fronto-cortical hypoactivity and attenuates anxiety and compulsive behaviors in rats.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Article
  15. Article
  16. Article
  17. Guanosine ameliorates positive symptoms of schizophreniaAmerican journal of translational research · 2021
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Eleanor H SimpsonDepartments of Psychiatry, Columbia University, New York, New York; Center for Neurobiology and Behavior, New York State Psychiatric Institute, New York, New York. Electronic address: Es534@columbia.edu.
Christoph KellendonkPharmacology, Columbia University, New York, New York; Division of Molecular Therapeutics (CK), New York State Psychiatric Institute, New York, New York.
Columbia University · USNew York Psychoanalytic Society and Institute · US

Funding

Dopamine Dysfunction in SchizophreniaP50MH086404 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI ABI-DARGHAM, ANISSA · 2010 to 2014
$9.4M
Medium Spiny Neuron Excitability and MotivationR01MH093672 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI KELLENDONK, CHRISTOPH · 2011 to 2020
$5.0M
NIMH NIH HHS P50 MH086404NIMH NIH HHS R01 MH093672
6 · The paper itself

Abstract

The dopamine hypothesis of schizophrenia is supported by a large number of imaging studies that have identified an increase in dopamine binding at the D

Indexed as

Disease Models, AnimalSchizophrenic PsychologyAnimalsBrainCorpus StriatumHumansMiceMice, TransgenicReceptors, Dopamine D2SchizophreniaUp-RegulationReceptors, Dopamine D2D(2) receptorDopamineMouse model, Negative symptomsSchizophreniaStriatal circuit function

Identifiers

PMID27720388
PMCPMC5121031
OpenAlexW2471473603

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.