Evidence map›Paper›PMID 27720246›Full record

ArticleJournal of critical care2017

Extra-central nervous system target for assessment and treatment in refractory anti-N-methyl-d-aspartate receptor encephalitis.

David W Nauen

Open access · greenAbstract readCase Reports
In one paragraph

Article in Journal of critical care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

David W NauenDepartment of Pathology, Johns Hopkins Hospital, Ross 512, 720 Rutland Ave, Baltimore, MD 21205. Electronic address: dwnauen@jhmi.edu.
Johns Hopkins Hospital · US

Funding

Research Education Program in Experimental NeuropathologyR25NS079185 · NINDS · JOHNS HOPKINS UNIVERSITY · PI TRONCOSO, JUAN · 2012 to 2017
$364k
NINDS NIH HHS R25 NS079185
6 · The paper itself

Abstract

Anti-N-methyl-d-aspartate-type glutamate receptor autoimmune encephalitis can arise in the setting of ovarian teratoma and often responds to resection. When it occurs in the absence of tumor, failure to respond to treatment may be more likely, and affected patients often require intensive care. To further understand the mechanisms and potential management, we present findings from an autopsy conducted on a young woman who died of refractory autoimmune encephalitis of this type. Rituximab was administered 70 days before death, and both 37 and 14 days before death, CD19

Indexed as

Anti-N-Methyl-D-Aspartate Receptor EncephalitisAutoantibodiesAutopsyBrainFemaleHippocampusHumansImmunologic FactorsMicrogliaPlasmapheresisRituximabTemporal LobeT-LymphocytesYoung AdultAutoantibodiesImmunologic FactorsRituximabAnti-NMDAR encephalitisAutopsyBiopsyNeurointensive careRefractory encephalitis

Identifiers

PMID27720246
PMCPMC5167652
OpenAlexW2523746664

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.