Observational studySurgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery2017
Early improvement in obstructive sleep apnea and increase in orexin levels after bariatric surgery in adolescents and young adults.
Observational study in Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00474318 (Teen-Longitudinal Assessment of Bariatric Surgery), which is not on this map. Cited by 23 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) Research Project
Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Bariatric surgery and obstructive sleep apnea: a systematic review and meta-analysis.Sleep & breathing = Schlaf & Atmung · 2023Pooled it
- Laparoscopic sleeve gastrectomy for obesity treatment in adolescents and young adults: a systematic review and meta-analysis.Langenbeck's archives of surgery · 2023Pooled it
- Improvement in Nocturnal Hypoxemia in Obese Patients with Obstructive Sleep Apnea after Bariatric Surgery: a Meta-Analysis.Obesity surgery · 2019Pooled it
- Long Biliopancreatic Limb Roux-En-Y Gastric Bypass Versus One-Anastomosis Gastric Bypass: a Randomized Controlled Study.Obesity surgery · 2023Trial
- The orexin system as a pharmacological target in inflammation: peripheral mechanisms and safety implications.Frontiers in pharmacology · 2026Review
- Comorbidity of obstructive sleep apnea and narcolepsy: A challenging diagnosis and complex management.Sleep medicine: X · 2024Review
- Estimating the prevalence and clinical causality of obstructive sleep apnea in paediatric narcolepsy patients.Sleep & breathing = Schlaf & Atmung · 2024Article
- Characteristics of adolescents referred for bariatric surgery in Abu Dhabi, United Arab Emirates.Frontiers in pediatrics · 2024Article
- Obesity, Bariatric Surgery and Obstructive Sleep Apnea-A Narrative Literature Review.Medicina (Kaunas, Lithuania) · 2023Review
- Outcome of Sleeve Gastrectomy Versus Roux-en-Y Gastric Bypass for Patients with Super Obesity (Body Mass Index > 50 kg/mObesity surgery · 2022Article
- Parental Perception of Weight Status for Adenotonsillectomy Patients.The Laryngoscope · 2021Article
- Debates in pediatric obstructive sleep apnea treatment.World journal of otorhinolaryngology - head and neck surgery · 2021Review
- Obstructive sleep apnea and early weight loss among adolescents undergoing bariatric surgery.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2021Article
- Development and application of an ethical framework for pediatric metabolic and bariatric surgery evaluation.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2021Article
- The Metabolic Rearrangements of Bariatric Surgery: Focus on Orexin-A and the Adiponectin System.Journal of clinical medicine · 2020Review
- Preoperative considerations for the pediatric patient undergoing metabolic and bariatric surgery.Seminars in pediatric surgery · 2020Review
- Alternative Approaches to Adenotonsillectomy and Continuous Positive Airway Pressure (CPAP) for the Management of Pediatric Obstructive Sleep Apnea (OSA): A Review.Sleep disorders · 2020Review
- Physical and Psychological Effects of Bariatric Surgery on Obese Adolescents: A Review.Frontiers in pediatrics · 2020Review
- Updates on management of pediatric obstructive sleep apnea.Pediatric investigation · 2019Review
- Short-Term Assessment of Obstructive Sleep Apnea Syndrome Remission Rate after Sleeve Gastrectomy: a Cohort Study.Obesity surgery · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundObstructive sleep apnea (OSA) associated with obesity is known to improve after bariatric surgery, but little is known about early changes in this condition after surgery.
objectivesTo study the clinical course of OSA after bariatric surgery
settingChildren's hospital in the United States
methodsAdolescents and young adults with obstructive sleep apnea undergoing vertical sleeve gastrectomy (n = 6) or gastric bypass (n = 1) were enrolled in this prospective study. Participants underwent formal polysomnography before and at 3 and 5 weeks after bariatric surgery. Anthropometric measurements and assay for orexin and leptin were also performed at study visits. Thirty-one adolescents who underwent 2 polysomnography studies that were 4 weeks apart served as control patients.
resultsBaseline mean (range) age of participants was 17.8 (15.4-20.7) years, 71% were male, with body mass index of 55.2 (41.3-61.6) kg/m
conclusionsThese observations suggest that OSA responds early and out of proportion to weight loss after metabolic and or bariatric surgery, thus weight independent factors may at least in part be responsible for early improvement in OSA postoperatively.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.