Evidence map›Paper›PMID 27720140›Full record

ReviewTrends in parasitology2017

Disease Centered Around Calcified Taenia solium Granuloma.

Theodore E Nash, Javier A Bustos, Hector H Garcia, Cysticercosis Working Group in Perú

Abstract readReview
In one paragraph

Review in Trends in parasitology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Calcified Neurocysticercosis: Understanding Dead (Not Necessarily Inactive) Parasites.The American journal of tropical medicine and hygiene · 2025
    Review
  6. Article
  7. Serum Proteomic Predictors of Calcification of Solitary Cysticercus Granuloma.The American journal of tropical medicine and hygiene · 2024
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Epileptogenesis in Common Parasitic Infections.Current neurology and neuroscience reports · 2022
    Review
  16. Article
  17. Article
  18. Frequency and Determinant Factors for Calcification in Neurocysticercosis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Theodore E NashLaboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.
Javier A BustosUnidad de Cisticercosis, Instituto Nacional de Ciencias Neurológicas, Lima, Peru. Electronic address: javier.bustos@jhu.edu.
Hector H GarciaUnidad de Cisticercosis, Instituto Nacional de Ciencias Neurológicas, Lima, Peru; Departamento de Ciencias Celulares y Moleculares, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima, Peru.
Cysticercosis Working Group in Perú

Funding

Studies of neurocysticercosis and animal cestode infectionsZIAAI000846 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI NASH, THEODORE · 2009 to 2020
$9.5M
Training in Parasitic Diseases and Central Nervous System Infections in Peru.D43TW001140 · FIC · UNIVERSIDAD PERUANA CAYETANO HEREDIA · PI GARCIA, HECTOR HUGO, GILMAN, ROBERT H · 1999 to 2025
$5.7M
Use of bisphosphonates to reduce the calcification process in animal models of cysticercosisR01AI116456 · NIAID · UNIVERSIDAD PERUANA CAYETANO HEREDIA · PI BUSTOS, JAVIER A · 2015 to 2019
$651k
FIC NIH HHS D43 TW001140NIAID NIH HHS R01 AI116456Wellcome Trust 091077
6 · The paper itself

Abstract

Taenia solium (the pork tapeworm) is present in most developing countries, where it is a frequent cause of seizures and other neurological disease. Parasitic larvae invade the human brain, establish, and eventually resolve, leaving a calcified scar. While these lesions are common in endemic regions, and most of these are clinically silent, a proportion of individuals with calcified cysticerci develop seizures from these lesions, and 30-65% of these cases are associated with perilesional edema (PE), likely due to host inflammation. This manuscript summarizes the importance, characteristics, natural history, and potential prevention and treatments of symptomatic calcified neurocysticercosis (NCC).

Indexed as

AnimalsBrainCalcinosisEdemaGranulomaHumansNeurocysticercosisSeizuresTaenia soliumcalcified granulomaepilepsyneurocysticercosisperilesional edemaseizures

Identifiers

PMID27720140
PMCPMC5203955

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.