Evidence map›Paper›PMID 27719760›Full record

ArticleeLife2016

BLOS2 negatively regulates Notch signaling during neural and hematopoietic stem and progenitor cell development.

Wenwen Zhou, Qiuping He, Chunxia Zhang, Xin He, Zongbin Cui, Feng Liu, Wei Li

Open access · goldAbstract read
In one paragraph

Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 74 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Wenwen ZhouState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
Qiuping HeUniversity of Chinese Academy of Sciences, Beijing, China.
Chunxia ZhangUniversity of Chinese Academy of Sciences, Beijing, China.
Xin HeState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
Zongbin CuiState Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Beijing, China.
Feng LiuUniversity of Chinese Academy of Sciences, Beijing, China.
Wei LiState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.ORCID 0000-0001-7430-6019
Chinese Academy of Sciences · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Notch signaling plays a crucial role in controling the proliferation and differentiation of stem and progenitor cells during embryogenesis or organogenesis, but its regulation is incompletely understood. BLOS2, encoded by the

Indexed as

Cell DifferentiationCell ProliferationSignal TransductionAnimalsHematopoietic Stem CellsMice, Inbred C57BLMice, KnockoutNeural Stem CellsProteinsReceptor, Notch1ZebrafishBLOS2 protein, mouseProteinsReceptor, Notch1BLOS2cell biologydevelopmental biologyendo-lysosomal traffickinghematopoiesismouseneurogenesisNotchstem and progenitor cell developmentstem cellszebrafish

Identifiers

PMID27719760
PMCPMC5094856
OpenAlexW2531798000

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.