Evidence map›Paper›PMID 27719759›Full record

ArticleeLife2016

Cortical flow aligns actin filaments to form a furrow.

Anne-Cecile Reymann, Fabio Staniscia, Anna Erzberger, Guillaume Salbreux, Stephan W Grill

Abstract read
In one paragraph

Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers.

0numbers the graph read from it
0cells of the map it votes in
96citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

96 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Asymmetric distribution of actin-related proteins in the earlybioRxiv : the preprint server for biology · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. microPublication biology · 2025
    Article
  15. Asymmetric fluctuations and self-folding of active interfaces.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  16. Actin polymerization counteracts prewetting of N-WASP on supported lipid bilayers.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  17. Article
  18. Article
  19. Non-Muscle Myosin II A: Friend or Foe in Cancer?International journal of molecular sciences · 2024
    Review
  20. Article

36 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anne-Cecile ReymannBiotechnology Center, Technische Universität Dresden, Dresden, Germany.ORCID 0000-0002-0517-5083
Fabio StanisciaMax Planck Institute for the Physics of Complex Systems, Dresden, Germany.
Anna ErzbergerMax Planck Institute for the Physics of Complex Systems, Dresden, Germany.
Guillaume SalbreuxMax Planck Institute for the Physics of Complex Systems, Dresden, Germany.
Stephan W GrillBiotechnology Center, Technische Universität Dresden, Dresden, Germany.

Funding

Cancer Research UK 21144Cancer Research UK FC001317European Research Council 281903Medical Research Council FC001317Wellcome Trust FC001317
6 · The paper itself

Abstract

Cytokinesis in eukaryotic cells is often accompanied by actomyosin cortical flow. Over 30 years ago, Borisy and White proposed that cortical flow converging upon the cell equator compresses the actomyosin network to mechanically align actin filaments. However, actin filaments also align via search-and-capture, and to what extent compression by flow or active alignment drive furrow formation remains unclear. Here, we quantify the dynamical organization of actin filaments at the onset of ring assembly in the

Indexed as

CytokinesisProtein MultimerizationActomyosinAnimalsCaenorhabditis elegansZygoteActomyosinactinactive matterbiophysicsC. eleganscell biologycytokinesiscytoskeletonnematic gelstructural biology

Identifiers

PMID27719759
PMCPMC5117871

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.