ArticleParasitology research1989
Protection against Trichinella spiralis induced by purified stage-specific surface antigens of infective larvae.
Article in Parasitology research, 1989. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed, 25 citations in OpenAlex.
- Vaccines as a Strategy to Control Trichinellosis.Frontiers in microbiology · 2022Review
- Immuno-proteomic analysis of Trichinella spiralis, T. pseudospiralis, and T. papuae extracts recognized by human T. spiralis-infected sera.Parasitology research · 2018Article
- Identification of diagnostic antigens from Trichinella spiralis.Parasitology research · 1992Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The stage-specific surface antigens of the infective larvae of Trichinella spiralis, isolated using an affinity column of monoclonal antibody (Mab) NIM-M1, consisted of four components with molecular weights of 72, 65, 52, and 47 kDa, respectively. These four components may have unique as well as shared structural features and appear to be products of the stichosome. When injected i.p. as an emulsion in complete Freund's adjuvant, the purified antigens induced protection against infection of BALB/c mice with T. spiralis, as assessed by reductions in both the muscle larvae load and the number of adult intestinal worms.
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Registered trials
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