Evidence map›Paper›PMID 27718158›Full record

ArticleAdvances in therapy2016

Perceptions of Oncologists, Healthcare Policy Makers, Patients and the General Population on the Value of Pharmaceutical Treatments in Oncology.

José A Sacristán, Luís Lizan, Marta Comellas, Pilar Garrido, Cristina Avendaño, Juan J Cruz-Hernández, Javier Espinosa, Tatiana Dilla

Open access · hybridAbstract read
In one paragraph

Article in Advances in therapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
7.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 10 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

José A SacristánMedical Department, Lilly, Madrid, Spain. sacristan_jose@lilly.com.
Luís LizanOutcomes'10, Castellón, Spain.
Marta ComellasOutcomes'10, Castellón, Spain.
Pilar GarridoMedical Oncology Department, University Hospital Ramon y Cajal, Madrid, Spain.
Cristina AvendañoClinical Pharmacology Department, Puerta de Hierro-Majadahonda Hospital, Madrid, Spain.
Juan J Cruz-HernándezSalamanca Institute for Biomedical Research, University Hospital Salamanca, Salamanca, Spain.
Javier EspinosaMedical Oncology Department, General Hospital Ciudad Real, Ciudad Real, Spain.
Tatiana DillaMedical Department, Lilly, Madrid, Spain.
Eli Lilly (Spain) · ESConsorcio Hospitalario Provincial de Castellón · ESHospital General Universitario de Ciudad Real · ESHospital Universitario Puerta de Hierro Majadahonda · ESHospital Universitario Ramón y Cajal · ESUniversitat Jaume I · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe purpose of this study was to explore the main factors explaining the relative weight of the different attributes that determine the value of oncologic treatments from the different perspectives of healthcare policy makers (HCPM), oncologists, patients and the general population in Spain.

methodsStructured interviews were conducted to assess: (1) the importance of the attributes on treatment choice when comparing a new cancer drug with a standard cancer treatment; (2) the importance of survival, quality of life (QoL), costs and innovation in cancer; and (3) the most worrying side effects related to cancer drugs.

resultsA total of 188 individuals participated in the study. For all participants, when choosing treatments, the best rated characteristics were greater efficacy, greater safety, treatment adaptation to patients' individual requirements and the rapid reincorporation of patients to their daily activities. There were important differences among participants in their opinion about survival, QoL and cost. In general, oncologists, patients, and the general population gave greater value to gains in QoL than healthcare policy makers. Compared to other participants healthcare policy makers gave greater importance to the economic impact related to oncology treatments.

conclusionsGains in QoL, survival, safety, cost and innovation are perceived differently by different groups of stakeholders. It is recommended to consider the perspective of different stakeholders in the assessment of a new cancer drugs to obtain more informed decisions when deciding on the most appropriate treatment to use.

fundingEli Lilly & Co, Madrid (Spain).

Indexed as

Antineoplastic AgentsMedical OncologyQuality of LifeAdministrative PersonnelAttitude of Health PersonnelCost-Benefit AnalysisFemaleHumansMaleNeoplasmsOncologistsSocial PerceptionSpainTherapies, InvestigationalAntineoplastic AgentsClinically meaningful outcomesInnovationOncologySpainValue

Identifiers

PMID27718158
PMCPMC5083772
OpenAlexW2529334869

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.