Evidence map›Paper›PMID 27718047›Full record

ArticleVirus genes2017

Generation and evaluation of a genetically attenuated Newcastle disease virus rGM-VIIm as a genotype-matched vaccine.

Minhua Sun, Bin Xiang, Yaling Li, Peng Xie, Shimin Gao, Yinfeng Kang, Pei Gao, Yanling Li, Zhaoxiong Wang, Jianpeng Liang and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Virus genes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Minhua SunCollege of Veterinary Medicine, South China Agricultural University, 483 Wushan Road, Guangzhou, Guangdong, China.
Bin XiangCollege of Veterinary Medicine, South China Agricultural University, 483 Wushan Road, Guangzhou, Guangdong, China.
Yaling LiCollege of Veterinary Medicine, South China Agricultural University, 483 Wushan Road, Guangzhou, Guangdong, China.
Peng XieCollege of Veterinary Medicine, South China Agricultural University, 483 Wushan Road, Guangzhou, Guangdong, China.
Shimin GaoCollege of Veterinary Medicine, South China Agricultural University, 483 Wushan Road, Guangzhou, Guangdong, China.
Yinfeng KangCollege of Veterinary Medicine, South China Agricultural University, 483 Wushan Road, Guangzhou, Guangdong, China.
Pei GaoCollege of Veterinary Medicine, South China Agricultural University, 483 Wushan Road, Guangzhou, Guangdong, China.
Yanling LiCollege of Veterinary Medicine, South China Agricultural University, 483 Wushan Road, Guangzhou, Guangdong, China.
Zhaoxiong WangCollege of Veterinary Medicine, South China Agricultural University, 483 Wushan Road, Guangzhou, Guangdong, China.
Jianpeng LiangCollege of Veterinary Medicine, South China Agricultural University, 483 Wushan Road, Guangzhou, Guangdong, China.
Deshui YuCollege of Veterinary Medicine, South China Agricultural University, 483 Wushan Road, Guangzhou, Guangdong, China.
Tao RenCollege of Veterinary Medicine, South China Agricultural University, 483 Wushan Road, Guangzhou, Guangdong, China. rentao6868@126.com.
Key Laboratory of Guangdong Province · CNSouth China Agricultural University · CNShanxi Agricultural University · CNYangtze University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite intensive vaccination campaigns, outbreaks of Newcastle disease (ND) have been frequently reported in China, especially of genotype VII that first emerged in the late 1990s. Given the dire need for vaccines against the circulating genotype VII virus, we developed an alternative method to recover a highly virulent recombinant GM (rGM) virus that involves a T7 system with a hammerhead ribozyme sequence introduced downstream of the T7 promoter. By changing the F

Indexed as

GenotypeVaccines, AttenuatedAnimalsAntibodies, ViralChickensDNA, ComplementaryGene OrderGenome, ViralImmunizationMutationNewcastle DiseaseNewcastle disease virusViral LoadViral VaccinesVirulenceVirus ReplicationAntibodies, ViralDNA, ComplementaryVaccines, AttenuatedViral VaccinesGenotype VIINewcastle disease virusReverse geneticsVaccine

Identifiers

PMID27718047
OpenAlexW2527901065

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.