SynthesisInternational orthopaedics2017
Total ankle arthroplasty versus ankle arthrodesis for the treatment of end-stage ankle arthritis: a meta-analysis of comparative studies.
Synthesis in International orthopaedics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 4 syntheses or guidelines pooled it, 135 citations in OpenAlex.
- A comparative study of modern total ankle replacement and ankle arthrodesis for ankle osteoarthritis at different follow-up times: a systematic review and meta-analysis.International orthopaedics · 2023Pooled it
- End-stage ankle osteoarthritis: arthroplasty offers better quality of life than arthrodesis with similar complication and re-operation rates-an updated meta-analysis of comparative studies.International orthopaedics · 2021Pooled it
- Open versus arthroscopic ankle arthrodesis: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2020Pooled it
- Comparison of the Efficiency and Safety of Total Ankle Replacement and Ankle Arthrodesis in the Treatment of Osteoarthritis: An Updated Systematic Review and Meta-analysis.Orthopaedic surgery · 2020Pooled it
- Early and Mid-term Effects of Ankle and Hindfoot Arthrodesis on Quality of Life.Foot & ankle orthopaedics · 2026Article
- Long-term Consequences of Total Ankle Replacement vs Ankle Fusion in England: A 25-Year National Population Study of 41 000 patients.Foot & ankle international · 2026Article
- Total ankle arthroplasty versus ankle arthrodesis in end-stage osteoarthritis: A meta-analysis of comparative outcomes.Journal of orthopaedics · 2025Review
- Study of Surgical Costs Associated With Tibiotalar Fusion.Foot & ankle orthopaedics · 2025Article
- Ankle Arthrodesis: Epidemiology, Etiology, and Complications in Diabetic vs Nondiabetic Patients Using US Nationwide Inpatient Sample Data.Foot & ankle orthopaedics · 2025Article
- Long-term Outcomes After Total Ankle Arthroplasty: A Systematic Review.Foot & ankle orthopaedics · 2024Article
- Midterm Results after Tibiotalar or Tibiotalocalcaneal Fusion Using an Ilizarov External Fixator.Clinics in orthopedic surgery · 2024Observational
- The INVISION Talar Component in Revision Total Ankle Arthroplasty: Analysis of Early Outcomes.Diagnostics (Basel, Switzerland) · 2024Article
- Outcomes of total ankle replacement - Current evidence.Journal of clinical orthopaedics and trauma · 2024Article
- Robotic-assisted foot and ankle surgery: a review of the present status and the future.Biomedical engineering letters · 2023Review
- A Novel Orthoplastic Reconstruction of Relapsed Clubfoot With Total Ankle Arthroplasty.Cureus · 2023Article
- Sport and Exercise Activity After Isolated Ankle Arthrodesis for Advanced-Stage Ankle Osteoarthritis: A Single-Center Retrospective Analysis.Foot & ankle orthopaedics · 2023Article
- Does ankle arthrodesis induce satisfactory changes in the medial longitudinal arch height of the foot for severe varus ankle arthritis?International orthopaedics · 2023Article
- Review
- Summary Report of the Arthritis Foundation and the American Orthopaedic Foot & Ankle Society's Symposium on Targets for Osteoarthritis Research: Part 2: Treatment Options.Foot & ankle orthopaedics · 2022Review
- Trends and Reported Complications in Ankle Arthroplasty and Ankle Arthrodesis in the State of New York, 2009-2018.Foot & ankle orthopaedics · 2022Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTotal ankle arthroplasty (TAA) and ankle arthrodesis (AA) are the main surgical treatment options for end-stage ankle arthritis. Although the superiority of each modality remains debated, there remains a lack of high-quality evidence-based studies, such as randomized controlled clinical trials, and meta-analyses of comparative studies. We performed a meta-analysis of comparative studies to determine whether there is a significant difference between these two procedures in terms of (i) clinical scores and patient satisfaction, (ii) re-operations, and (iii) complications.
methodsWe conducted a comprehensive search in the MEDLINE, EMBASE, and Cochrane library databases. Only retrospective or prospective comparative studies were included in this meta-analysis. The literature search, data extraction, and quality assessment were conducted by two independent reviewers. The primary outcomes were clinical scores and patient satisfaction. We also investigated the prevalence of complications and the re-operation rate.
resultsTen comparative studies were included (four prospective and six retrospective studies). There were no significant differences between the two procedures in the American Orthopaedic Foot and Ankle Society ankle-hindfoot score, Short Form-36 physical component summary and mental component summary scores, visual analogue scale for pain, and patient satisfaction rate. The risk of re-operation and major surgical complications were significantly increased in the TAA group.
conclusionsThe meta-analysis revealed that TAA and AA could achieve similar clinical outcomes, whereas the incidence of re-operation and major surgical complication was significantly increased in TAA. Further studies of high methodological quality with long-term follow-up are required to confirm our conclusions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.