Evidence map›Paper›PMID 27717559›Full record

ArticleActa orthopaedica et traumatologica turcica2016

Peritoneum and omentum are natural reservoirs for chondrocytes of osteochondral autografts: A comparative animal study.

Kadir Buyukdogan, Mahmut Nedim Doral, Onur Bilge, Egemen Turhan, Gazi Huri, Mustafa Fevzi Sargon

Abstract read
In one paragraph

Article in Acta orthopaedica et traumatologica turcica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kadir BuyukdoganHacettepe University, Faculty of Medicine, Department of Orthopaedics and Traumatology, Ankara, Turkey.
Mahmut Nedim DoralHacettepe University, Faculty of Medicine, Department of Orthopaedics and Traumatology, Ankara, Turkey. Electronic address: mndoral@gmail.com.
Onur BilgeNecmettin Erbakan University, Meram School of Medicine, Department of Orthopaedics and Traumatology, Turkey.
Egemen TurhanHacettepe University, Faculty of Medicine, Department of Anatomy, Ankara, Turkey.
Gazi HuriHacettepe University, Faculty of Medicine, Department of Anatomy, Ankara, Turkey.
Mustafa Fevzi SargonHacettepe University, Faculty of Medicine, Department of Anatomy, Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe purpose of this study was to investigate the effects of the omentum, peritoneum, paratenon and skeletal muscle on the proliferation of the cartilage tissue using rabbit model as an in vivo culture medium.

methods6 months old forty-five New Zealand rabbits were randomized into omentum, peritoneum, muscle, and Achilles paratenon groups. Standard sized osteochondral grafts were harvested from right knees and immediately placed into the specified tissues. Control group was fresh cartilage at the end of follow-up. After five months, samples were collected and evaluated macroscopically by measuring their dimensions (vertical = D1, horizontal = D2, and depth = D3) and volumes, and histologically by counting the chondrocyte number using camera lucida method.

resultsMacroscopically, increase in mean values for D1 and D2 dimensions of specimens from paratenon and omentum compared to pretransplant dimensions was statistically significant (p < 0.05). Although, volume measurements were higher in omentum and peritoneum group compared to pretransplant dimensions, increase was not significant (p > 0.05). Histologically, mean chondrocyte count was 14.0 ± 0.6 in fresh articular cartilage. Mean chondrocyte counts were 14.4 ± 0.9 in omentum group, 15.4 ± 1.0 in peritoneum group, 9.7 ± 1.3 in muscle group and 9.2 ± 0.4 in Achilles paratenon group respectively. However, mean chondrocyte counts were higher in samples of omentum and peritoneum group compared to fresh articular cartilage, increase was not statistically significant (p > 0.05). DISCUSSION: Transplantation of the cartilage grafts into mesothelium enhanced the chondrocyte counts and volumes compared with the pretransplant measurements. Mesothelium may have the potential to be used as an in vivo culture medium for osteochondral tissue growth.

Indexed as

AnimalsCartilage, ArticularChondrocytesMaleOmentumPeritoneumRabbitsRandom AllocationTissue PreservationTransplantation, AutologousCartilage preservationChondrocyteKneeMesothelium

Identifiers

PMID27717559
PMCPMC6197382

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.