Evidence map›Paper›PMID 27717407›Full record

Trial reportBMC research notes2016

A feasibility study of the clinical effectiveness and cost-effectiveness of individual cognitive behavioral therapy for panic disorder in a Japanese clinical setting: an uncontrolled pilot study.

Yoichi Seki, Shinobu Nagata, Takayuki Shibuya, Naoki Yoshinaga, Mizue Yokoo, Hanae Ibuki, Noriko Minamitani, Muga Kusunoki, Yasushi Inada, Nobuko Kawasoe and 6 more

Erratum issuedAbstract readClinical Trial
In one paragraph

Trial report in BMC research notes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Yoichi SekiUnited Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University School of Medicine, Chiba University and University of Fukui, Suita, Japan. yoichi-seki@hotmail.co.jp.
Shinobu NagataDepartment of Cognitive Behavioral Physiology, Chiba University Graduate School of Medicine, Chiba, Japan.
Takayuki ShibuyaDepartment of Cognitive Behavioral Physiology, Chiba University Graduate School of Medicine, Chiba, Japan.
Naoki YoshinagaDepartment of Cognitive Behavioral Physiology, Chiba University Graduate School of Medicine, Chiba, Japan.
Mizue YokooDepartment of Cognitive Behavioral Physiology, Chiba University Graduate School of Medicine, Chiba, Japan.
Hanae IbukiDepartment of Cognitive Behavioral Physiology, Chiba University Graduate School of Medicine, Chiba, Japan.
Noriko MinamitaniDepartment of Cognitive Behavioral Physiology, Chiba University Graduate School of Medicine, Chiba, Japan.
Muga KusunokiInada Clinic, Osaka, Japan.
Yasushi InadaInada Clinic, Osaka, Japan.
Nobuko KawasoeClinic Adachi, Gifu, Japan.
Soichiro AdachiClinic Adachi, Gifu, Japan.
Kensuke YoshimuraDepartment of Psychiatry, Graduate School of Medicine, Chiba University, Chiba, Japan.
Michiko NakazatoDepartment of Cognitive Behavioral Physiology, Chiba University Graduate School of Medicine, Chiba, Japan.
Masaomi IyoDepartment of Psychiatry, Graduate School of Medicine, Chiba University, Chiba, Japan.
Akiko NakagawaResearch Center for Child Mental Development, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba-shi, Chiba, 260-8670, Japan.
Eiji ShimizuResearch Center for Child Mental Development, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba-shi, Chiba, 260-8670, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn Japan, cognitive behavioral therapy (CBT) for panic disorder (PD) is not well established. Therefore, a feasibility study of the clinical effectiveness and cost-effectiveness of CBT for PD in a Japanese clinical setting is urgently required. This was a pilot uncontrolled trial and the intervention consisted of a 16-week CBT program. The primary outcome was Panic Disorder Severity Scale (PDSS) scores. Quality of life was assessed using the EuroQol's EQ-5D questionnaire. Assessments were conducted at baseline, 8 weeks, and at the end of the study. Fifteen subjects completed outcome measures at all assessment points.

resultsAt post-CBT, the mean reduction in PDSS scores from baseline was -6.6 (95 % CI 3.80 to -9.40, p < 0.001) with a Cohen's d = 1.77 (95 % CI 0.88-2.55). Ten (66.7 %) participants achieved a 40 % or greater reduction in PDSS. By calculating areas under the curve for EQ-5D index changes, we estimated that patients gained a minimum of 0.102 QALYs per 1 year due to the CBT.

conclusionsThis study demonstrated that individual CBT for PD may be useful in Japanese clinical settings but further randomized control trials are needed.

trial registrationUMIN-CTR UMIN000022693 (retrospectively registered).

Indexed as

Cost-Benefit AnalysisAdultCognitive Behavioral TherapyFeasibility StudiesFemaleHumansJapanMaleMiddle AgedPanic DisorderPilot ProjectsCognitive behavioral therapyJapanesePanic disorderQALYQuality of life

Identifiers

PMID27717407
PMCPMC5055685

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.