Evidence map›Paper›PMID 27717330›Full record

ArticleBMC gastroenterology2016

Role of vitamin D

Francesca Uberti, Claudio Bardelli, Vera Morsanuto, Sabrina Ghirlanda, Claudio Molinari

Open access · goldAbstract read
In one paragraph

Article in BMC gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Vitamin D protects human melanocytes against oxidative damage by activation of Wnt/β-catenin signaling.Laboratory investigation; a journal of technical methods and pathology · 2018
    Article
  10. Vitamin D Receptor Is Necessary for Mitochondrial Function and Cell Health.International journal of molecular sciences · 2018
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Francesca UbertiLaboratory of Physiology, Department of Translational Medicine, University of Piemonte Orientale, via Solaroli 17, Novara, 28100, Italy. francesca.uberti@med.uniupo.it.
Claudio BardelliLaboratory of Physiology, Department of Translational Medicine, University of Piemonte Orientale, via Solaroli 17, Novara, 28100, Italy.
Vera MorsanutoLaboratory of Physiology, Department of Translational Medicine, University of Piemonte Orientale, via Solaroli 17, Novara, 28100, Italy.
Sabrina GhirlandaLaboratory of Physiology, Department of Translational Medicine, University of Piemonte Orientale, via Solaroli 17, Novara, 28100, Italy.
Claudio MolinariLaboratory of Physiology, Department of Translational Medicine, University of Piemonte Orientale, via Solaroli 17, Novara, 28100, Italy.
Università degli Studi del Piemonte Orientale “Amedeo Avogadro” · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastric diseases are a worldwide problem in modern society, as reported in the USA, in the range of 0.5-2 episodes/year/person and an incidence of 5-100 episodes/1000/week according to seasons and age. There is convincing evidence that oxidative stress is involved in the pathogenesis of acute gastric injury. Acid secreted from gastric parietal cells determines mucosal injuries which in turn cause inflammation and oxidative stress. Consequent inflammation produces free radicals by mitochondria thus causing lipid peroxidation, oxidative and acidic stress, which can lead to cell apoptosis. Vitamin D

methodsThis study was planned to assess whether vitamin D

resultsIn case of oxidative stress or acidity condition the stimulation with Grisù® alone caused an improvement of cell viability and a reduction of ROS production on epithelial gastric cells. In addition, the adhesion time of the cells was improved. All these effects were increased by the presence of vitamin D

conclusionsThese results suggest that Grisù® in combination with vitamin D

Indexed as

AlginatesAntioxidantsApoptosisAutophagyCell AdhesionCell LineCells, CulturedCell SurvivalCholecalciferolDrug Therapy, CombinationEpithelial CellsGastric MucosaGastrointestinal AgentsHumansOxidative StressProtective AgentsAlginatesAntioxidantsCholecalciferolGastrointestinal AgentsProtective AgentsReactive Oxygen SpeciesVitaminsActive vitamin DGastric acidGastroprotective drugsOxidative stress

Identifiers

PMID27717330
PMCPMC5054561
OpenAlexW2528704405

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.