ArticleAdvanced healthcare materials2016
Mucus-Penetrating Nanosuspensions for Enhanced Delivery of Poorly Soluble Drugs to Mucosal Surfaces.
Article in Advanced healthcare materials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Biophysical and aerodynamic properties of a peptide targeting the A-kinase anchoring function of PI3Kγ for pulmonary cAMP modulation.Scientific reports · 2026Article
- Voriconazole-Loaded Nanohydrogels Towards Optimized Antifungal Therapy for Cystic Fibrosis Patients.Pharmaceutics · 2025Article
- The mucosal protein corona in local nanoparticle drug delivery.Cell biomaterials · 2025Article
- Locally administered nanosuspension increases delivery of estradiol for the treatment of vaginal atrophy in mice.Drug delivery and translational research · 2025Article
- Hypotonic, gel-forming delivery system for vaginal drug administration.Journal of controlled release : official journal of the Controlled Release Society · 2024Article
- Mucosal Penetrative Polymeric Micelle Formulations for Insulin Delivery to the Respiratory Tract.International journal of nanomedicine · 2024Article
- Design of Quorum Sensing Inhibitor-Polymer Conjugates to PenetrateACS macro letters · 2023Article
- Development of nintedanib nanosuspension for inhaled treatment of experimental silicosis.Bioengineering & translational medicine · 2023Article
- Mucus-Penetrating Silk Fibroin-Based Nanotherapeutics for Efficient Treatment of Ulcerative Colitis.Biomolecules · 2022Article
- Preclinical evaluation of a hypotonic docetaxel nanosuspension formulation for intravesical treatment of non-muscle-invasive bladder cancer.Drug delivery and translational research · 2021Article
- Oral delivery of proteins and peptides: Challenges, status quo and future perspectives.Acta pharmaceutica Sinica. B · 2021Review
- Next generation strategies for preventing preterm birth.Advanced drug delivery reviews · 2021Review
- Avoiding a Sticky Situation: Bypassing the Mucus Barrier for Improved Local Drug Delivery.Trends in molecular medicine · 2021Review
- Enhancing nanoparticle penetration through airway mucus to improve drug delivery efficacy in the lung.Expert opinion on drug delivery · 2021Review
- Enhanced drug delivery to the reproductive tract using nanomedicine reveals therapeutic options for prevention of preterm birth.Science translational medicine · 2021Article
- Comparative study of mucoadhesive and mucus-penetrative nanoparticles based on phospholipid complex to overcome the mucus barrier for inhaled delivery of baicalein.Acta pharmaceutica Sinica. B · 2020Article
- Sticking to the Problem: Engineering Adhesion in Molecular Endoscopic Imaging.Cellular and molecular bioengineering · 2020Review
- Tuning the PEG surface density of the PEG-PGA enveloped Octaarginine-peptide Nanocomplexes.Drug delivery and translational research · 2020Article
- Development of a mucoinert progesterone nanosuspension for safer and more effective prevention of preterm birth.Journal of controlled release : official journal of the Controlled Release Society · 2019Article
- Mucus-penetrating budesonide nanosuspension enema for local treatment of inflammatory bowel disease.Biomaterials · 2018Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
Mucus-penetrating nanosuspensions, consisting of pure hydrophobic therapeutics with dense muco-inert coatings that enable particles to effectively bypass the mucus barrier, demonstrate superior drug distribution and absorption at mucosal surfaces. With significantly increased drug load compared to polymeric systems and established clinical translation of nanosuspensions-based products, mucus-penetrating nanosuspensions are a promising vehicle for improving mucosal delivery of poorly soluble drugs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.