Evidence map›Paper›PMID 27717093›Full record

ArticleNMR in biomedicine2016

Spatial variability and reproducibility of GABA-edited MEGA-LASER 3D-MRSI in the brain at 3 T.

Petra Hnilicová, Michal Považan, Bernhard Strasser, Ovidiu C Andronesi, Martin Gajdošík, Ulrike Dydak, Jozef Ukropec, Dušan Dobrota, Siegfried Trattnig, Wolfgang Bogner

Open access · bronzeAbstract read
In one paragraph

Article in NMR in biomedicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 36 citations in OpenAlex.

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  7. Contribution of macromolecules to brainNMR in biomedicine · 2021
    Article
  8. Review
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  11. Motion correction in magnetic resonance spectroscopy.Magnetic resonance in medicine · 2020
    Review
  12. Review
  13. Effect of Age on GABA+ and Glutathione in a Pediatric Sample.AJNR. American journal of neuroradiology · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 3 countries.

Petra HnilicováComenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Biomedical Center Martin, Division of Neurosciences, Martin, Slovakia.
Michal PovažanChristian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria.
Bernhard StrasserHigh Field MR Center, Medical University of Vienna, Department of Biomedical Imaging and Image-guided Therapy, Vienna, Austria.ORCID 0000-0001-9542-3855
Ovidiu C AndronesiMassachusetts General Hospital, Harvard Medical School, Martinos Center for Biomedical Imaging, Boston, Massachusetts, USA.
Martin GajdošíkHigh Field MR Center, Medical University of Vienna, Department of Biomedical Imaging and Image-guided Therapy, Vienna, Austria.
Ulrike DydakPurdue University, School of Health Sciences, West Lafayette, IN, USA, Indiana University School of Medicine, Department of Radiology and Imaging Sciences, Indianapolis, Indiana, USA.
Jozef UkropecInstitute of Experimental Endocrinology, Biomedical Research Center, Slovak Academy of Sciences, Obesity Section, Diabetes and Metabolic Disease Laboratory, Bratislava, Slovakia.
Dušan DobrotaComenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Department of Medical Biochemistry, Martin, Slovakia.
Siegfried TrattnigChristian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria.
Wolfgang BognerHigh Field MR Center, Medical University of Vienna, Department of Biomedical Imaging and Image-guided Therapy, Vienna, Austria. wolfgang.bogner@meduniwien.ac.at.
Medical University of Vienna · ATChristian Doppler Laboratory for Thermoelectricity · ATComenius University Bratislava · SKHarvard University · USIndiana University Health · USMartin University Hospital · SKSlovak Academy of Sciences · SK

Funding

Neuroimaging for Early Diagnosis of Manganese Toxicity in Humans and RodentsR01ES020529 · NIEHS · PURDUE UNIVERSITY · PI DYDAK, ULRIKE · 2011 to 2015
$2.0M
NIEHS NIH HHS R01 ES020529
6 · The paper itself

Abstract

The reproducibility of gamma-aminobutyric acid (GABA) quantification results, obtained with MRSI, was determined on a 3 T MR scanner in healthy adults. In this study, a spiral-encoded, GABA-edited, MEGA-LASER MRSI sequence with real-time motion-scanner-instability corrections was applied for robust 3D mapping of neurotransmitters in the brain. In particular, the GABA

Indexed as

AlgorithmsArtifactsAdultBrainComputer SystemsFemalegamma-Aminobutyric AcidHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMaleMolecular ImagingNeurotransmitter AgentsReproducibility of ResultsSensitivity and SpecificitySignal Processing, Computer-Assistedgamma-Aminobutyric AcidNeurotransmitter Agentsacquisition methodsMEGA editingMRS and MRSI methodsneurotransmittersnormal brainreproducibility

Identifiers

PMID27717093
PMCPMC5095789
OpenAlexW2529224260

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.