Evidence map›Paper›PMID 27716992›Full record

ArticleClinical cardiology2016

Bone mineral density is associated with left ventricular diastolic function in women.

Rui-Tao Wang, Xue-Song Li, Ji-Rong Zhang, Yuxiang Sun, Kai-Jiang Yu, Tiemin Liu

Open access · bronzeAbstract read
In one paragraph

Article in Clinical cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Beware! Some crucial information is left unattended on our myocardial perfusion scans!Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  3. Bone in heart failure.Journal of cachexia, sarcopenia and muscle · 2020
    Review
  4. Article
  5. Article
  6. Article
  7. Skeletal consequences of heart failure.Women's health (London, England)
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Rui-Tao WangDepartment of Internal Medicine, Third Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, China.
Xue-Song LiDepartment of Orthopedics, First Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, China.
Ji-Rong ZhangDepartment of Geriatrics, Second Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, China.
Yuxiang SunChildren's Nutrition Research Center, Huffington Center on Aging, Departments of Pediatrics & Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas.
Kai-Jiang YuDepartment of Intensive Care, Third Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, China.
Tiemin LiuDivision of Hypothalamic Research, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, Texas.
Harbin Medical University · CNChildren's Nutrition Research Center at Baylor College of Medicine · USSouthwestern Medical Center · USThird Affiliated Hospital of Harbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLow bone mineral density (BMD) and left ventricular (LV) diastolic function are associated with heart failure. However, little is known about the association between BMD and LV diastolic function. HYPOTHESIS: BMD is independently related to LV diastolic function in women.

methodsWe conducted a cross-sectional study of 432 women. Brachial-ankle pulse wave velocity (baPWV) and BMD measurements were performed. LV diastolic function and structure were assessed by echocardiographic examination.

resultsBaPWV and the percentage of LV diastolic dysfunction increased with progressive bone loss. Moreover, partial correlation analysis demonstrated that BMD at spine L2-4 and at femoral neck were correlated with baPWV and LV diastolic function parameters after adjusting covariates. Multivariate logistic regression analysis revealed that osteoporosis was independently associated with LV diastolic dysfunction in women.

conclusionsOsteoporosis is independently associated with LV diastolic dysfunction in women. A prospective study is needed to elucidate the effects of BMD on cardiac function in women.

Indexed as

Bone DensitySurveys and QuestionnairesAgedChinaCross-Sectional StudiesDiastoleEchocardiographyFemaleHumansIncidenceOsteoporosisProspective StudiesVentricular Dysfunction, LeftVentricular Function, LeftechocardiographyImaging

Identifiers

PMID27716992
PMCPMC6490870
OpenAlexW2529697323

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.