Evidence map›Paper›PMID 27716949›Full record

ArticlePhotochemistry and photobiology2017

Skin Exposure to Ultraviolet B Rapidly Activates Systemic Neuroendocrine and Immunosuppressive Responses.

Cezary Skobowiat, Arnold E Postlethwaite, Andrzej T Slominski

Abstract read
In one paragraph

Article in Photochemistry and photobiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Beneficial health effects of ultraviolet radiation: expert review and conference report.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Review
  9. Review
  10. Review
  11. Article
  12. Photo-neuro-immuno-endocrinology: How the ultraviolet radiation regulates the body, brain, and immune system.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Vitamin D Signaling in Psoriasis: Pathogenesis and Therapy.International journal of molecular sciences · 2022
    Review
  20. Clinical perspectives on the age-related increase of immunosuppressive activity.Journal of molecular medicine (Berlin, Germany) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Cezary SkobowiatDepartment of Pharmacodynamics and Molecular Pharmacology, Faculty of Pharmacy, The Ludwik Rydygier Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.
Arnold E PostlethwaiteDivision of Connective Tissue Diseases, Department of Medicine, University of Tennessee, Memphis, TN.
Andrzej T SlominskiDepartments of Dermatology and Pathology, University of Alabama at Birmingham, Birmingham, AL.
Collegium Medicum in Bydgoszcz · PLMemphis VA Medical Center · USUniversity of Alabama at Birmingham · US

Funding

Novel Biosynthetic Pathway for Secosteroids and the SkinR01AR052190 · NIAMS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI POSTLETHWAITE, ARNOLD E, SLOMINSKI, ANDRZEJ T · 2006 to 2013
$2.2M
Role of Exogenous Melatonin in Skin BiologyR01AR056666 · NIAMS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI SLOMINSKI, ANDRZEJ T · 2011 to 2015
$1.6M
Mechanism of action of 20-hydroxyvitamin D3 in dermal fibroblastsR21AR066505 · NIAMS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI SLOMINSKI, ANDRZEJ T · 2014 to 2015
$355k
NIAMS NIH HHS R01 AR052190NIAMS NIH HHS R01 AR056666NIAMS NIH HHS R21 AR066505
6 · The paper itself

Abstract

The back skin of C57BL/6 mice was exposed to a single 400 mJ cm

Indexed as

Adrenocorticotropic HormoneAnimalsbeta-EndorphinCorticosteroneCorticotropin-Releasing HormoneCulture Media, ConditionedFemaleHypothalamo-Hypophyseal SystemInterferon-gammaMice, Inbred C57BLPituitary-Adrenal SystemSkinUltraviolet RaysAdrenocorticotropic Hormonebeta-EndorphinCorticosteroneCorticotropin-Releasing HormoneCulture Media, ConditionedInterferon-gamma

Identifiers

PMID27716949
PMCPMC5366283
OpenAlexW2523848246

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.