ArticleJournal of Alzheimer's disease : JAD2017
Potentially Inappropriate Medication in Community-Dwelling Primary Care Patients who were Screened Positive for Dementia.
Article in Journal of Alzheimer's disease : JAD, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01401582 (Dementia), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Dementia: Life- and Personcentered Help in Germany
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Global prevalence of polypharmacy and potentially inappropriate medication in older patients with dementia: a systematic review and meta-analysis.Frontiers in pharmacology · 2023Pooled it
- Healthcare Needs Patterns and Pattern-Predicting Factors in Dementia: Results of the Comprehensive, Computerized Unmet Needs Assessment from the Randomized, Controlled Interventional Trial InDePendent.Journal of Alzheimer's disease : JAD · 2024Trial
- Tasks and Activities of an Effective Collaborative Dementia Care Management Program in German Primary Care.Journal of Alzheimer's disease : JAD · 2022Trial
- Translation of Collaborative Dementia Care Management into Different Healthcare Settings: Study Protocol for a Multicenter Implementation Trial (DCM:IMPact).Journal of Alzheimer's disease reports · 2022Trial
- Effectiveness and Safety of Dementia Care Management in Primary Care: A Randomized Clinical Trial.JAMA psychiatry · 2017Trial
- Dementia and comorbidities in primary care: a scoping review.BMC primary care · 2023Article
- Potentially inappropriate medications according to PRISCUS list and FORTA (Fit fOR The Aged) classification in geriatric psychiatry: a cross-sectional study.Journal of neural transmission (Vienna, Austria : 1996) · 2022Article
- Alzheimer Disease: Standard of Diagnosis, Treatment, Care, and Prevention.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022Article
- Prevalence and Factors that Influence Potentially Inappropriate Medication Use among Thai Elderly in Primary Care Settings.Canadian geriatrics journal : CGJ · 2021Article
- An investigation of new medications initiation during ambulatory care visits in patients with dementia.Exploratory research in clinical and social pharmacy · 2021Article
- Healthcare Utilization in Different Stages among Patients with Dementia: A Nationwide Population-Based Study.International journal of environmental research and public health · 2021Article
- Potentially inappropriate medication in older psychiatric patients.European journal of clinical pharmacology · 2021Article
- Current use of anticholinergic medications in a large naturalistic sample of psychiatric patients.Journal of neural transmission (Vienna, Austria : 1996) · 2021Article
- One-year persistence of potentially inappropriate medication use in older adults: A population-based study.British journal of clinical pharmacology · 2020Article
- Use of Anti-Dementia Drugs Reduces the Risk of Potentially Inappropriate Medications: A Secondary Analysis of a Nationwide Survey of Prescribing Pharmacies.Dementia and geriatric cognitive disorders · 2020Article
- The Changes in Medication Prescribing Among the Older People with Cognitive Impairment in the Acute Care Setting.Clinical interventions in aging · 2020Article
- AgeWell.de - study protocol of a pragmatic multi-center cluster-randomized controlled prevention trial against cognitive decline in older primary care patients.BMC geriatrics · 2019Article
- Potentially inappropriate medication use among hypertensive older African-American adults.BMC geriatrics · 2018Observational
- Longitudinal patterns of potentially inappropriate medication use following incident dementia diagnosis.Alzheimer's & dementia (New York, N. Y.) · 2018Article
- Drug-related problems in community-dwelling primary care patients screened positive for dementia.International psychogeriatrics · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPotentially inappropriate medication (PIM) in older people is a risk factor for adverse drug effects. This risk is even higher in older people with dementia (PWD).
objectiveOur study aimed to determine (1) the prevalence of PIM among primary care patients who were screened positive for dementia and (2) the sociodemographic and clinical variables associated with the use of PIM.
methodsDelpHi-MV (Dementia: life- and person-centered help in Mecklenburg-Western Pomerania) is a general practitioner-based, cluster-randomized, controlled intervention study to implement and evaluate an innovative concept of collaborative dementia care management in Germany. The comprehensive baseline assessment includes a home medication review. The present analyses are based on the data from 448 study participants (age 70+, DemTect <9). PIMs were identified using the list of Potentially Inappropriate Medications in the Elderly (Priscus).
results(1) A total of 99 study participants (22%) received at least one PIM. The highest prevalence was found for antidepressants, benzodiazepines, and analgetics. The most frequently prescribed PIMs were amitriptyline, etoricoxib, and doxazosin. (2) Use of a PIM was significantly associated with a diagnosis of a mental or behavioral disorder.
conclusionsThe prescription rate of PIMs for community-dwelling PWD was comparable with the rates found for the general population of older people in Germany (20-29%). Antidepressants with anticholinergic properties and long-acting benzodiazepines were the most prescribed PIMs, despite having an unfavorable benefit-risk ratio. This high prevalence of PIM prescriptions in a vulnerable population of PWD indicates that standard care for dementia should include careful medication review and management.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.