Evidence map›Paper›PMID 27716640›Full record

ArticlePhysics in medicine and biology2016

A promising new mechanism of ionizing radiation detection for positron emission tomography: modulation of optical properties.

Li Tao, Henry M Daghighian, Craig S Levin

Abstract read
In one paragraph

Article in Physics in medicine and biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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  9. Effect of CZT system characteristics on Compton scatter event recovery.IEEE transactions on radiation and plasma medical sciences · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Li TaoDepartment of Electrical Engineering, Stanford University, Stanford, CA, USA.
Henry M DaghighianDepartment of Radiology, Stanford University, Stanford, CA, USA.
Craig S LevinDepartment of Electrical Engineering, Stanford University, Stanford, CA, USA.

Funding

Probing optical property changes in photonic materials for faster timing in PETR21EB015155 · NIBIB · STANFORD UNIVERSITY · PI LEVIN, CRAIG S · 2013 to 2014
$400k
NIBIB NIH HHS R21 EB015155
6 · The paper itself

Abstract

Using conventional scintillation detection, the fundamental limit in positron emission tomography (PET) time resolution is strongly dependent on the inherent temporal variances generated during the scintillation process, yielding an intrinsic physical limit for the coincidence time resolution of around 100 ps. On the other hand, modulation mechanisms of the optical properties of a material exploited in the optical telecommunications industry can be orders of magnitude faster. In this paper we borrow from the concept of optics pump-probe measurement to for the first time study whether ionizing radiation can produce modulations of optical properties, which can be utilized as a novel method for radiation detection. We show that a refractive index modulation of approximately [Formula: see text] is induced by interactions in a cadmium telluride (CdTe) crystal from a 511 keV photon source. Furthermore, using additional radionuclide sources, we show that the amplitude of the optical modulation signal varies linearly with both the detected event rate and average photon energy of the radiation source.

Indexed as

Optics and PhotonicsPhotonsRadiation, IonizingCadmium CompoundsMonte Carlo MethodPositron-Emission TomographyTelluriumCadmium Compoundscadmium tellurideTellurium

Identifiers

PMID27716640
PMCPMC5117889

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.