ArticlePhysics in medicine and biology2016
Depth-resolved 3D visualization of coronary microvasculature with optical microangiography.
Article in Physics in medicine and biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Pericytes in mouse heart.Frontiers in physiology · 2025Article
- Optical coherence tomography-enabled classification of the human venoatrial junction.Journal of biomedical optics · 2025Article
- Quantifying Microvascular Structure in Healthy and Infarcted Rat Hearts Using Optical Coherence Tomography Angiography.IEEE transactions on medical imaging · 2024Article
- Stacking thick perfusable human microvascular grafts enables dense vascularity and rapid integration into infarcted rat hearts.Biomaterials · 2023Article
- Article
- Shexiang Tongxin Dropping Pills Promote Macrophage Polarization-Induced Angiogenesis Against Coronary Microvascular DysfunctionFrontiers in pharmacology · 2022Article
- Sweat the small stuff: The human microvasculature and heart disease.Microcirculation (New York, N.Y. : 1994) · 2021Review
- Guided vascularization in the rat heart leads to transient vessel patterning.APL bioengineering · 2020Article
- Optical coherence tomography imaging of cardiac substrates.Quantitative imaging in medicine and surgery · 2019Review
- Patterned human microvascular grafts enable rapid vascularization and increase perfusion in infarcted rat hearts.Nature communications · 2019Article
- Integrated approaches to spatiotemporally directing angiogenesis in host and engineered tissues.Acta biomaterialia · 2018Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
In this study, we propose a novel implementation of optical coherence tomography-based angiography combined with ex vivo perfusion of fixed hearts to visualize coronary microvascular structure and function. The extracorporeal perfusion of Intralipid solution allows depth-resolved angiographic imaging, control of perfusion pressure, and high-resolution optical microangiography. The imaging technique offers new opportunities for microcirculation research in the heart, which has been challenging due to motion artifacts and the lack of independent control of pressure and flow. With the ability to precisely quantify structural and functional features, this imaging platform has broad potential for the study of the pathophysiology of microvasculature in the heart as well as other organs.
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Registered trials
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