Evidence map›Paper›PMID 27716486›Full record

ArticleMolecular cell2016

53BP1 Goes Back to Its p53 Roots.

Daniel Durocher, Laurence Pelletier

Abstract readComment
PubMed Publisher
In one paragraph

Article in Molecular cell, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Daniel DurocherThe Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital and Department of Molecular Genetics, University of Toronto, Toronto, ON M5G 1X5, Canada. Electronic address: durocher@lunenfeld.ca.
Laurence PelletierThe Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital and Department of Molecular Genetics, University of Toronto, Toronto, ON M5G 1X5, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this issue of Molecular Cell, Cuella-Martin et al. (2016) revisit the role of 53BP1 in p53-dependent responses and find that these functions are separable from its widely known function in DNA repair.

Indexed as

DNA Breaks, Double-StrandedDNA RepairBinding SitesChromatinGene Expression RegulationHumansMCF-7 CellsPromoter Regions, GeneticProtein BindingProtein MultimerizationSignal TransductionTumor Suppressor p53-Binding Protein 1Tumor Suppressor Protein p53Ubiquitin ThiolesteraseChromatinTP53BP1 protein, humanTumor Suppressor p53-Binding Protein 1Tumor Suppressor Protein p53Ubiquitin ThiolesteraseUSP28 protein, human

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.