Evidence map›Paper›PMID 27716382›Full record

ArticleJournal of cardiothoracic surgery2016

Gender differences in outcomes following isolated coronary artery bypass grafting: long-term results.

Francesco Nicolini, Antonella Vezzani, Daniela Fortuna, Giovanni Andrea Contini, Davide Pacini, Davide Gabbieri, Claudio Zussa, Rossana De Palma, Tiziano Gherli, RERIC (Registro dell’Emilia Romagna degli Interventi Cardiochirurgici) Investigators

Abstract readMulticenter Study
In one paragraph

Article in Journal of cardiothoracic surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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  14. Impact of gender on 10-year outcome after coronary artery bypass grafting.Interactive cardiovascular and thoracic surgery · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Francesco NicoliniClinical and Experimental Medicine Department, Cardiac Surgery Unit, University of Parma, Parma, Italy. francesco.nicolini@unipr.it.
Antonella VezzaniSurgery Department, Cardiac Surgery Unit, Parma Hospital, Parma, Italy.
Daniela FortunaRegional Agency for Health and Social Care, Bologna, Italy.
Giovanni Andrea ContiniSurgery Department, Cardiac Surgery Unit, Parma Hospital, Parma, Italy.
Davide PaciniCardio-Thoracic-Vascular Department, University Hospital S.Orsola-Malpighi, Bologna, Italy.
Davide GabbieriDepartment of Clinical Cardiology and Thoraco Vascular Surgery, Hesperia Hospital, Bologna, Italy.
Claudio ZussaDepartment of Cardiology and Cardiac Surgery, Villa Maria Cecilia Hospital, Bologna, Ravenna, Italy.
Rossana De PalmaRegional Agency for Health and Social Care, Bologna, Italy.
Tiziano GherliClinical and Experimental Medicine Department, Cardiac Surgery Unit, University of Parma, Parma, Italy.
RERIC (Registro dell’Emilia Romagna degli Interventi Cardiochirurgici) Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe main purpose of this study was to evaluate the impact of gender on outcomes after isolated coronary artery bypass grafting, in terms of 5-year rates of overall death, cardiac-related death, myocardial infarction, re-hospitalization, repeat percutaneous or surgical revascularization, stroke, new pacemaker implantation, postoperative renal failure, heart failure and need for long-term care.

methodsTwo propensity-score matched cohorts, each of 1331 patients, undergoing isolated surgical coronary revascularization at the regional public and private centers of Emilia-Romagna region (Italy) from January 1st 2003 to December 31th 2013, were used to compare long-term outcomes of male (5976 patients) versus female gender (1332 patients).

resultsIn the matched cohort, males received significantly more bypass grafts (3.0 ± 1.0 vs 2.8 ± 1.0, p = 0.001). Left internal mammary artery use and total arterial revascularization were similarly performed in both matched subgroups. Both groups reported similar cumulative rate of all-cause, cardiac-related mortality and stroke at five years. Females experienced significantly higher rate of myocardial infarction, and not significantly higher occurrence of heart failure, and need for long-term care. Males experienced significantly higher rate of cumulative re-hospitalization and higher need for pacemaker implantation. Female gender was not an independent predictor of death at long-term follow-up.

conclusionsWomen are more likely to be readmitted with myocardial infarction and congestive heart failure after CABG but experience survival similar to that observed in men. Female gender was not an independent risk factor for mortality. Prevention of new occurrence of postoperative myocardial infarction and enhancement of complete coronary revascularization should be future endpoints.

Indexed as

Sex FactorsAgedAged, 80 and overCoronary Artery BypassCoronary DiseaseFemaleFollow-Up StudiesHeart FailureHumansItalyLong-Term CareMaleMyocardial InfarctionPacemaker, ArtificialPatient ReadmissionPercutaneous Coronary InterventionCoronary artery bypass graftingCoronary artery diseaseGender

Identifiers

PMID27716382
PMCPMC5045636

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.