ArticleBMC infectious diseases2016
Seroprevalence of human immunodeficiency virus, hepatitis B and C viruses, and Treponema pallidum infections among blood donors at Shiyan, Central China.
Article in BMC infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Pooled it
- Pooled it
- Seroprevalence and trend of human immunodeficiency virus among blood donors in Ethiopia: a systematic review and meta-analysis.BMC infectious diseases · 2019Pooled it
- Blood Unit Discard Rates Due to Transfusion-Transmissible Infections and Non-Infectious Causes and Their Associated Factors in Eastern and Northeastern Parts of Amhara Regional State, Ethiopia: A Retrospective Cross-Sectional Study From 2022-2025.Health science reports · 2026Article
- Prevalence of Transfusion-Transmitted Viral Infections Among Blood Donors in Riyadh, Saudi Arabia: A Comparative Analysis of Nucleic Acid Testing and Serological Screening.Journal of clinical medicine · 2026Article
- Epidemiological and Population Characteristics of Seroprevalence of TTIs Among Voluntary Blood Donors - Guangzhou City, Guangdong Province, China, 2014-2023.China CDC weekly · 2025Article
- Seroprevalence and Risk Factors of Transfusion-Related Infections Among Blood Donors in Central China During and After the COVID-19 Pandemic: Evaluation of TTIs in Shiyan.Journal of tropical medicine · 2025Article
- Risk Factors of Transfusion Transmissible Infections among Blood Donors at Karongi Regional Centre for Blood Transfusion in Rwanda.Rwanda journal of medicine and health sciences · 2023Article
- Trends in serological markers of transfusion transmissible infections in blood donations at the Bamenda Hospital-based Blood Service, Cameroon.Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine · 2021Article
- Retrospective Study of the Seroprevalence of HIV, HCV, and HBV in Blood Donors at a Blood Bank of Western Mexico.Pathogens (Basel, Switzerland) · 2021Article
- Correlation between serology and nucleic acid amplification test in blood donors who are reactive for hepatitis B virus, hepatitis C and human immunodeficiency virus and evaluation of the epidemiological profile of infected people in blood centers in the State of Paraná.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2021Article
- Human Immunodeficiency Virus and Syphilis Among Blood Donors at Western Oromia, Ethiopia.Journal of blood medicine · 2021Article
- Transfusion transmitted infections among male blood donors of White Nile State, Sudan: Screening of the current seroprevalence and distribution.BMC research notes · 2020Article
- Prevalence of sexually transmitted infections among foreigners living in Guangzhou, China: a cross-sectional study (2010-2017).BMC infectious diseases · 2020Article
- Seroprevalence of markers of hepatitis C virus exposure and associated factors in adults aged 18-39 years in the Arctic Russian city of Arkhangelsk: a cross-sectional study.International journal of circumpolar health · 2019Article
- Demographic characteristics of transfusion-transmitted infections among blood donors in China.BMC infectious diseases · 2019Article
- Seroprevalence of transfusion transmitted infections among blood donors in Gash Barka Zonal Blood Transfusion Center, Barentu, Eritrea, 2014 through 2017.BMC hematology · 2019Article
- An Update on the Global Epidemiology of Syphilis.Current epidemiology reports · 2018Article
- The Burden and Trend of Blood-Borne Pathogens among Asymptomatic Adult Population in Akwatia: A Retrospective Study at the St. Dominic Hospital, Ghana.Journal of tropical medicine · 2017Article
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Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOrdinary screening of transfusion-transmissible infections (TTIs) among blood donors is essential for blood transfusion. Although there is several TTIs studies focus on human immunodeficiency virus, hepatitis B and C viruses, and Treponema pallidum infections in China, it is no data to illustrate any firm conclusion from Shiyan City, Central China. It aims to verify the seroprevalence of TTIs among blood donors at Shiyan.
methodsA retrospective analysis of blood donors' information was conducted for the presence of HIV, HBV, HCV and T. pallidum. Logistic regression analysis was used to demonstrate risk factors including age, gender and occupation associated with them. The variation tendency in seroprevalence of these TTIs over the study period was evaluated by Cochran-Armitage trend test.
resultsOf 211 639 blood donors, 2 858 (1.35 %) had serological evidence of TTIs. The seroprevalence of HIV, HBV, HCV and T. pallidum were 0.08 %, 0.51 %, 0.20 % and 0.57 %, respectively. However, the co-infection prevalence of TTIs has not been detected. The HIV seropositivity significantly increased among female donors (OR = 1.63, P < 0.001) and farmers (OR = 2.02, P = 0.020). Significantly increased HBV seropositivity was only observed framers (OR = 1.87, P <0.001) compared to workers. Analogously, significantly increased HCV seropositivity was observed among farmers (OR = 2.59, P < 0.001), students (OR = 2.43, P < 0.001), merchants (OR = 1.70, P = 0.014) and others (OR = 1.78, P =0.001). The T. pallidum seroprevalence was notably increased among female (OR = 1.54, P < 0.001), and farmers (OR = 1.70, P <0.001). Moreover, significantly increasing trends of HIV (Z = -6.88, P < 0.01), HBV (Z = -4.52, P < 0.01), HCV (Z = -4.16, P < 0.01) and T. pallidum (Z = -1.36, P < 0.01) seropositivity were observed over the study period.
conclusionsIt originally offers a substantial prevalence of TTIs among blood donors at Shiyan, Central China. Severe blood donor selection and all-inclusive screening of blood are highly recommended. It might be helpful for developing and updating guidance for blood safety.
trial registrationRetrospectively registered.
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