Evidence map›Paper›PMID 27716144›Full record

SynthesisBMC public health2016

Prevalence of osteoporosis in China: a meta-analysis and systematic review.

Peng Chen, Zhanzhan Li, Yihe Hu

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04086784 (3D-printed Porous Titanium Alloy Cages Versus PEEK Cages), which is not on this map. Cited by 177 papers, 18 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
177citing papers in PubMed, 18 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04086784 unknown statusnot on this mapstarted 2020, after this paper: background citation

3D-printed Porous Titanium Alloy Cages Versus PEEK Cages: Pedicle Screw Loosening Rate and Fusion Rate in Patients With Osteoporosis

TypeobservationalSponsorPeking University Third HospitalRan2020 to 2022Enrolled90ConditionsOsteoporosis, Degenerative Disc Disease, Degenerative Lumbar Spinal Stenosis, Degeneration Spine
3 · Its place in the literature

Who cites it

177 citing papers in PubMed, 18 syntheses or guidelines pooled it.

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  6. Prevalence of osteoporosis and incidence of related fractures in developed economies in the Asia Pacific region: a systematic review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2023
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  16. Effects of isoflavone interventions on bone mineral density in postmenopausal women: a systematic review and meta-analysis of randomized controlled trials.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020
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117 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Peng ChenDepartment of Orthopedic, Xiangya Hospital, Central South University, No.87, Xiangya Road, Kaifu District, Changsha City, Hunan Province, 410008, China.
Zhanzhan LiDepartment of Oncology, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Yihe HuDepartment of Orthopedic, Xiangya Hospital, Central South University, No.87, Xiangya Road, Kaifu District, Changsha City, Hunan Province, 410008, China. yihehumed@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe conducted a systematic review and meta-analysis to obtain a reliable estimation of the prevalence of osteoporosis in China and to characterize its epidemiology.

methodsWe identified relevant studies via a search of literature published from 2003 to October 2015 in the PubMed, Web of Science, China National Knowledge Infrastructure, Wanfang and Weipu databases. Both Chinese and WHO criteria were considered acceptable for the diagnosis of osteoporosis. Prevalence estimates were obtained using random effects models. Meta-regression analysis was used to explore the sources of heterogeneity, and publication bias was evaluated by visually inspecting funnel plots.

resultsOverall, 69 articles were included in this study. An obvious increase in the prevalence of osteoporosis was identified over the past 12 years (prevalence of 14.94 % before 2008 and 27.96 % during the period spanning 2012-2015). The prevalence of osteoporosis was higher in females than in males (25.41 % vs. 15.33 %) and increased with age. Osteoporosis prevalence was higher in rural than in urban areas (20.87 % vs. 23.92 %) and higher in southern than in northern areas (23.17 % vs. 20.13 %). At present, the pooled prevalence of osteoporosis in people aged 50 years and older was more than twice the pooled prevalence identified in 2006 (34.65 % vs. 15.7 %). The application of different diagnostic criteria could have an impact on prevalence estimation (19.7 % vs. 29.3 %). Meta-regression suggested that study setting also influenced the estimation of point prevalence (P = 0.022).

conclusionsThe prevalence of osteoporosis in China has increased over the past 12 years, affecting more than one-third of people aged 50 years and older. The prevalence of osteoporosis increased with age and was higher in females than in males. Prevention and control measures have become all the more important given the increase in osteoporosis prevalence, and three-step prevention programmes should be implemented.

Indexed as

AdultAge DistributionAsian PeopleChinaFemaleHumansMaleMiddle AgedOsteoporosisPrevalencePublication BiasRegression AnalysisRural PopulationSex DistributionUrban PopulationChinaCross-sectional studyMeta-analysisOsteoporosisPrevalence

Identifiers

PMID27716144
PMCPMC5048652

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.