Trial reportBMC cardiovascular disorders2016
Rationale and Design of the CREDENCE Trial: computed TomogRaphic evaluation of atherosclerotic DEtermiNants of myocardial IsChEmia.
Trial report in BMC cardiovascular disorders, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02173275 (Computed TomogRaphic Evaluation of Atherosclerotic DEtermiNants of Myocardial IsChEmia), which is not on this map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Computed TomogRaphic Evaluation of Atherosclerotic DEtermiNants of Myocardial IsChEmia (The CREDENCE Trial)
Who cites it
11 citing papers in PubMed, 29 citations in OpenAlex.
- Diagnostic Performance of a Novel AI-Guided Coronary Computed Tomography Algorithm for Predicting Myocardial Ischemia (AI-QCTJournal of the Society for Cardiovascular Angiography & Interventions · 2026Article
- First comparison between artificial intelligence-guided coronary computed tomography angiography versus single-photon emission computed tomography testing for ischemia in clinical practice.Coronary artery disease · 2025Article
- Cardiac Radiofrequency Ablation Exacerbates Myocardial Injury through Pro-Inflammatory Response and Pro-Oxidative Stress in Elderly Patients with Persistent Atrial Fibrillation.Current vascular pharmacology · 2024Article
- Diabetes, Atherosclerosis, and Stenosis by AI.Diabetes care · 2023Article
- Artificial intelligence and machine learning: the resurgence of the industrial revolution by robots.Open heart · 2022Article
- Improved Functional Assessment of Ischemic Severity Using 3D Printed Models.Frontiers in cardiovascular medicine · 2022Article
- Relationship of age, atherosclerosis and angiographic stenosis using artificial intelligence.Open heart · 2021Article
- End-to-End, Pixel-Wise Vessel-Specific Coronary and Aortic Calcium Detection and Scoring Using Deep Learning.Diagnostics (Basel, Switzerland) · 2021Article
- Article
- [Noninvasive numerical simulation of coronary fractional flow reserve based on lattice Boltzmann method].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2018Article
- Prognostic Value and Therapeutic Perspectives of Coronary CT Angiography: A Literature Review.BioMed research international · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors at 16 institutions in 6 countries.
Funding
Abstract
backgroundCoronary computed tomography angiography (CCTA) allows for non-invasive assessment of obstructive coronary artery disease (CAD) beyond measures of stenosis severity alone. This assessment includes atherosclerotic plaque characteristics (APCs) and calculation of fractional flow reserve (FFR) from CCTA (FFR
methodsCREDENCE will enroll adult individuals with symptoms suspicious of CAD referred for non-emergent invasive coronary angiography (ICA), but without known CAD. All participants will undergo CCTA, MPS, ICA and FFR. FFR will be performed for lesions identified at the time of ICA to be ≥40 and <90 % stenosis, or those clinically indicated for evaluation. Study analyses will focus on diagnostic performance of CCTA versus MPS against invasive FFR reference standard. An integrated stenosis-APC-FFR DISCUSSION: CREDENCE will determine the performance of integrated CCTA metric compared to integrated MPS measure for diagnosis of vessel-specific ischemia. If proven successful, this study may reduce the number of missed diagnoses and help to optimally predict ischemia-causing lesions.
trial registrationClinicalTrials.gov, NCT02173275 . Registered on June 23, 2014.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.