Evidence map›Paper›PMID 27715904›Full record

ArticleSubstance abuse

Recent incarceration and buprenorphine maintenance treatment outcomes among human immunodeficiency virus-positive patients.

Daniel P Riggins, Chinazo O Cunningham, Yuming Ning, Aaron D Fox

Abstract readMulticenter Study
In one paragraph

Article in Substance abuse. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Routes of non-traditional entry into buprenorphine treatment programs.Substance abuse treatment, prevention, and policy · 2020
    Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Daniel P Rigginsa Albert Einstein College of Medicine , New York , New York , USA.
Chinazo O Cunninghama Albert Einstein College of Medicine , New York , New York , USA.
Yuming Ninga Albert Einstein College of Medicine , New York , New York , USA.
Aaron D Foxa Albert Einstein College of Medicine , New York , New York , USA.

Funding

Core-010UL1TR001073 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KELLER, MARLA J, SHAMOON, HARRY · 2013 to 2017
$21.3M
Immunology/Pathology CoreP30AI051519 · NIAID · YESHIVA UNIVERSITY · PI KIM, MIMI Y · 2003 to 2013
$18.6M
Abstinence Reinforcing Contingency Management to Suppress HIV Viral LoadR01DA032110 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI CUNNINGHAM, CHINAZO · 2011 to 2015
$3.6M
HIV and Substance Abuse Clinical Addiction Research and Education (CARE) ProgramR25DA023021 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI ARNSTEN, JULIA H. · 2007 to 2014
$2.7M
CLINICAL ADDICTION RESEARCH AND EDUCATION (CARE) PROGRAMR25DA014551 · NIDA · MONTEFIORE MEDICAL CENTER (BRONX, NY) · PI ARNSTEN, JULIA H. · 2002 to 2005
$1.3M
Buprenorphine Facilitated Access and Supportive Treatment in Former InmatesK23DA034541 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI FOX, AARON D · 2012 to 2016
$913k
Mentoring researchers on drug abuse and HIVK24DA036955 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI CUNNINGHAM, CHINAZO · 2014 to 2019
$911k
Resilience in HIV infected drug usersR03DA039727 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI CUNNINGHAM, CHINAZO · 2016 to 2017
$167k
NCATS NIH HHS UL1 TR001073NIAID NIH HHS P30 AI051519NIDA NIH HHS K23 DA034541NIDA NIH HHS K24 DA036955NIDA NIH HHS R01 DA032110NIDA NIH HHS R03 DA039727NIDA NIH HHS R25 DA014551NIDA NIH HHS R25 DA023021
6 · The paper itself

Abstract

backgroundOpioid use disorder is a common cause of morbidity and mortality among people living with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS). Buprenorphine maintenance treatment (BMT) is an effective means of therapy, but patients with recent criminal justice involvement may need more support during BMT than other patients. The authors hypothesized that recently incarcerated BMT patients who initiated treatment in primary care would have poorer treatment outcomes than those who were not recently incarcerated.

methodsInvestigators analyzed data from a multisite cohort study of BMT integrated into HIV care. Patients were stratified by self-reported incarceration in the 30 days before initiation of BMT. The outcomes of interest were 6- and 12-month treatment retention and self-reported opioid use. Investigators used multivariable logistic regression and hierarchical linear model, respectively, to evaluate the association between recent incarceration and these outcomes while adjusting for potential confounding variables.

resultsAmong 305 BMT patients living with HIV/AIDS, 39 (13%) reported recent incarceration. Patients with recent incarceration (vs. without) were more likely to be homeless, unemployed, and previously diagnosed with mental illness. Recent incarceration was not significantly associated with differences in 6-month (odds ratio [OR] = 0.95; 95% confidence interval [CI] = 0.46-1.98) and 12-month (OR = 0.57; 95% CI = 0.27-1.18) treatment retention or in self-reported opioid use (OR = 0.99; 95% CI = 0.51-1.92) after adjustment for potential confounding variables.

conclusionsThose with incarceration in the 30 days prior to BMT initiation were more likely to be homeless, unemployed, and previously diagnosed with mental illness than those without recent incarceration. However, no significant difference in self-reported opioid use or 6-month or 12-month retention in treatment was detected between those with and without recent incarceration. Future studies should confirm these findings with larger sample sizes. Encouraging formerly incarcerated individuals with opioid use disorder to initiate evidence-based treatments, including BMT, should be part of efforts to confront the opioid addiction epidemic in the United States.

Indexed as

AdultBuprenorphineCase-Control StudiesFemaleHIV InfectionsHumansLongitudinal StudiesMaleMiddle AgedOpiate Substitution TreatmentOpioid-Related DisordersPatient CompliancePrisonersRisk FactorsTreatment OutcomeBuprenorphineBuprenorphinecriminal justiceHIVincarcerationopiate addictionopiate substitution treatmentopioid-related disorders

Identifiers

PMID27715904
PMCPMC5303565

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.