Evidence map›Paper›PMID 27715711›Full record

ReviewRadiographics : a review publication of the Radiological Society of North America, Inc

Strategies to Increase Cancer Detection: Review of True-Positive and False-Negative Results at Digital Breast Tomosynthesis Screening.

Katrina E Korhonen, Susan P Weinstein, Elizabeth S McDonald, Emily F Conant

Abstract readReview
In one paragraph

Review in Radiographics : a review publication of the Radiological Society of North America, Inc. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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  15. Calcifications at Digital Breast Tomosynthesis: Imaging Features and Biopsy Techniques.Radiographics : a review publication of the Radiological Society of North America, Inc
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Katrina E KorhonenFrom the Division of Breast Imaging, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce St, 1 Silverstein, Philadelphia, PA 19104.
Susan P WeinsteinFrom the Division of Breast Imaging, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce St, 1 Silverstein, Philadelphia, PA 19104.
Elizabeth S McDonaldFrom the Division of Breast Imaging, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce St, 1 Silverstein, Philadelphia, PA 19104.
Emily F ConantFrom the Division of Breast Imaging, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce St, 1 Silverstein, Philadelphia, PA 19104.

Funding

Penn Center for Innovation in Personalized Breast ScreeningU54CA163313 · NCI · UNIVERSITY OF PENNSYLVANIA · PI ARMSTRONG, KATRINA, SCHNALL, MITCHELL D. · 2011 to 2017
$7.4M
NCI NIH HHS U54 CA163313
6 · The paper itself

Abstract

Digital breast tomosynthesis (DBT) represents a valuable addition to breast cancer screening by decreasing recall rates while increasing cancer detection rates. The increased accuracy achieved with DBT is due to the quasi-three-dimensional format of the reconstructed images and the ability to "scroll through" breast tissue in the reconstructed images, thereby reducing the effect of tissue superimposition found with conventional planar digital mammography. The margins of both benign and malignant lesions are more conspicuous at DBT, which allows improved lesion characterization, increased reader confidence, and improved screening outcomes. However, even with the improvements in accuracy achieved with DBT, there remain differences in breast cancer conspicuity by mammographic view. Early data suggest that breast cancers may be more conspicuous on craniocaudal (CC) views than on mediolateral oblique (MLO) views. While some very laterally located breast cancers may be visualized on only the MLO view, the increased conspicuity of cancers on the CC view compared with the MLO view suggests that DBT screening should be performed with two-view imaging. Even with the improved conspicuity of lesions at DBT, there may still be false-negative studies. Subtle lesions seen on only one view may be discounted, and dense and/or complex tissue patterns may make some cancers occult or extremely difficult to detect. Therefore, radiologists should be cognizant of both perceptual and cognitive errors to avoid potential pitfalls in lesion detection and characterization.

Indexed as

Breast NeoplasmsDiagnostic ErrorsEarly Detection of CancerEvidence-Based MedicineFalse Negative ReactionsFalse Positive ReactionsFemaleHumansImaging, Three-DimensionalMammographyRadiation DosageRadiographic Image EnhancementReproducibility of ResultsSensitivity and Specificity

Identifiers

PMID27715711
PMCPMC5161511

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.