Evidence map›Paper›PMID 27715454›Full record

ArticleVirulence2017

Diverse profiles of N-acyl-homoserine lactones in biofilm forming strains of Cronobacter sakazakii.

Niharika Singh, Amrita Patil, Asmita A Prabhune, Mamta Raghav, Gunjan Goel

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virulence, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

  1. TheThe Journal of biological chemistry · 2020
    Article
  2. Review
  3. Analysis of the Molecular Diversity AmongFrontiers in microbiology · 2020
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Niharika Singha Department of Biotechnology and Bioinformatics , Jaypee University of Information Technology , Solan , India.
Amrita Patilb Biochemical Science Division , National Chemical Laboratory , Pune , India.
Asmita A Prabhuneb Biochemical Science Division , National Chemical Laboratory , Pune , India.
Mamta Raghava Department of Biotechnology and Bioinformatics , Jaypee University of Information Technology , Solan , India.
Gunjan Goela Department of Biotechnology and Bioinformatics , Jaypee University of Information Technology , Solan , India.
Jaypee University of Information Technology · INNational Chemical Laboratory · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study investigates the role of quorum sensing (QS) molecules expressed by C. sakazakii in biofilm formation and extracellular polysaccharide expression. The QS signaling was detected using Chromobacterium violaceum 026 and Agrobacterium tumefaciens NTL4(pZLR4) based bioassay. Long chain N-acyl-homoserine lactones (AHLs) with C6- C18 chain length were identified using High Performance Liquid Chromatography and Liquid Chromatography-High Resolution Mass Spectrometry. A higher Specific Biofilm Formation (SBF) index (p < 0.05) with the presence of genes associated with cellulose biosynthesis (bcsA, bcsC and bcsG) was observed in the strains. AHLs and their mechanisms can serve as novel targets for developing technologies to eradicate and prevent biofilm formation by C. sakazakii.

Indexed as

Quorum SensingAcyl-ButyrolactonesAgrobacterium tumefaciensBiofilmsBiological AssayChromatography, High Pressure LiquidChromobacteriumCronobacter sakazakiiMass SpectrometryPolysaccharides, BacterialAcyl-ButyrolactonesPolysaccharides, Bacterialbiofilmcronobacter sakazakiiextracellular polymeric substancesmass spectroscopyN-acyl homoserine lactonequorum sensingvirulence

Identifiers

PMID27715454
PMCPMC5411235
OpenAlexW2529810379

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.