Evidence map›Paper›PMID 27715026›Full record

ArticleJournal of the American Chemical Society2016

Therapeutic Delivery of H

Chadwick R Powell, Jeffrey C Foster, Benjamin Okyere, Michelle H Theus, John B Matson

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Nanomotor-based HBioactive materials · 2024
    Article
  7. Article
  8. Enzyme-Triggered Chemodynamic Therapy via a Peptide-HAngewandte Chemie (International ed. in English) · 2023
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. HBiomolecules · 2021
    Review
  17. Article
  18. Amino acid-based HChemical communications (Cambridge, England) · 2021
    Article
  19. The Journal of organic chemistry · 2021
    Article
  20. Trends in HAntioxidants (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chadwick R PowellDepartment of Chemistry, Virginia Tech , Blacksburg, Virginia 24061, United States.
Jeffrey C FosterDepartment of Chemistry, Virginia Tech , Blacksburg, Virginia 24061, United States.
Benjamin OkyereDepartment of Biomedical Sciences and Pathobiology, Virginia-Maryland Regional College of Veterinary Medicine , Duck Pond Drive, Blacksburg, Virginia 24061, United States.
Michelle H TheusDepartment of Biomedical Sciences and Pathobiology, Virginia-Maryland Regional College of Veterinary Medicine , Duck Pond Drive, Blacksburg, Virginia 24061, United States.
John B MatsonDepartment of Chemistry, Virginia Tech , Blacksburg, Virginia 24061, United States.

Funding

Mechanisms Regulating Cerebral Arteriogenesis and NeurorestorationR01NS096281 · NINDS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI THEUS, MICHELLE LEE · 2016 to 2020
$1.9M
COLLATERAL FORMATION AND REMODELING AFTER ISCHEMIC STROKER15NS081623 · NINDS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI THEUS, MICHELLE LEE · 2013 to 2013
$483k
NINDS NIH HHS R01 NS096281NINDS NIH HHS R15 NS081623
6 · The paper itself

Abstract

Carbonyl sulfide (COS) is a gas that may play important roles in mammalian and bacterial biology, but its study is limited by a lack of suitable donor molecules. We report here the use of N-thiocarboxyanhydrides (NTAs) as COS donors that release the gas in a sustained manner under biologically relevant conditions with innocuous peptide byproducts. Carbonic anhydrase converts COS into H

Indexed as

Drug CarriersGreen Chemistry TechnologyHydrazinesHydrogen SulfidePolymersSulfur Oxidescarbonyl sulfideDrug CarriersHydrazinesHydrogen SulfidePolymersSulfur Oxidesthiocarbohydrazide

Identifiers

PMID27715026
PMCPMC5074078

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.