Evidence map›Paper›PMID 27714805›Full record

ArticleJournal of cellular physiology2017

Challenging of AS160/TBC1D4 Alters Intracellular Lipid milieu in L6 Myotubes Incubated With Palmitate.

Agnieszka Mikłosz, Bartłomiej Łukaszuk, Małgorzata Żendzian-Piotrowska, Justyna Brańska-Januszewska, Halina Ostrowska, Adrian Chabowski

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cellular physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
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  5. Insulin-Stimulated Muscle Glucose Uptake and Insulin Signaling in Lean and Obese Humans.The Journal of clinical endocrinology and metabolism · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Agnieszka MikłoszDepartment of Physiology, Medical University of Bialystok, Bialystok, Poland.
Bartłomiej ŁukaszukDepartment of Physiology, Medical University of Bialystok, Bialystok, Poland.
Małgorzata Żendzian-PiotrowskaDepartment of Hygiene, Epidemiology and Ergonomics, Medical University of Bialystok, Bialystok, Poland.
Justyna Brańska-JanuszewskaDepartment of Biology, Medical University of Bialystok, Bialystok, Poland.
Halina OstrowskaDepartment of Biology, Medical University of Bialystok, Bialystok, Poland.
Adrian ChabowskiDepartment of Physiology, Medical University of Bialystok, Bialystok, Poland.
Medical University of Białystok · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Akt substrate of 160 kDa (AS160) is a key regulator of GLUT4 translocation from intracellular depots to the plasma membrane in myocytes. Likely, AS160 also controls LCFAs transport, which requires relocation of fatty acid transporters. The aim of the present study was to determine the impact of AS160 knockdown on lipid milieu in L6 myotubes incubated with palmitate (PA). Therefore, we compared two different settings, namely: 1) AS160 knockdown prior to palmitate incubation (pre-PA-silencing, AS160

Indexed as

AnimalsBiological TransportCD36 AntigensCell LineFatty Acid-Binding ProteinsFatty Acid Transport ProteinsGTPase-Activating ProteinsInsulin ResistanceLipid MetabolismMitochondria, MuscleMuscle Fibers, SkeletalPalmitic AcidPhosphorylationProto-Oncogene Proteins c-aktRatsRNA InterferenceCD36 AntigensCd36 protein, ratFatty Acid-Binding ProteinsFatty Acid Transport ProteinsGot2 protein, ratGTPase-Activating ProteinsPalmitic AcidProto-Oncogene Proteins c-aktRNA, MessengerSlc27a1 protein, ratSlc27a4 protein, ratTBC1D4 protein, rat

Identifiers

PMID27714805
PMCPMC5485047
OpenAlexW2528499059

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.