ArticleEpilepsia2016
A feasibility trial of an Internet-delivered and transdiagnostic cognitive behavioral therapy treatment program for anxiety, depression, and disability among adults with epilepsy.
Article in Epilepsia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Measures of Subjective Memory for People with Epilepsy: A Systematic Review of Measurement Properties.Neuropsychology review · 2024Pooled it
- Quality of life during usual epilepsy care for anxiety or depression symptoms: Secondary patient-reported outcomes in a randomized trial of remote assessment methods.Epilepsy research · 2024Trial
- Internet-delivered cognitive behaviour therapy for chronic health conditions: self-guided versus team-guided.Journal of behavioral medicine · 2022Trial
- Guided internet-delivered cognitive-behaviour therapy for persons with spinal cord injury: a feasibility trial.Spinal cord · 2020Trial
- An intensive education program for caregivers ameliorates anxiety, depression, and quality of life in patients with drug-resistant temporal lobe epilepsy and mesial temporal sclerosis who underwent cortico-amygdalohippocampectomy.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2020Trial
- Adaptive actions and treatment outcomes in transdiagnostic internet-delivered cognitive behaviour therapy for chronic health conditions.Internet interventions · 2026Article
- Feasibility and impact of virtual reality exposure therapy on epilepsy-specific anxiety: Phase 3 of the AnxEpiVR pilot clinical trial.Epilepsy & behavior reports · 2026Article
- Comparative effectiveness of digital mental healthcare models for adults with epilepsy: A study protocol of a randomized controlled trial.Epilepsia open · 2024Article
- Effect of cognitive behavioral intervention on anxiety, depression, and quality of life in patients with epilepsy.American journal of translational research · 2022Article
- Managing depression and anxiety in people with epilepsy: A survey of epilepsy health professionals by the ILAE Psychology Task Force.Epilepsia open · 2021Article
- Clinical Study on Electronic Medical Neuroelectric Stimulation Based on the Internet of Things to Treat Epilepsy Patients with Anxiety and Depression.Journal of healthcare engineering · 2021Article
- The Management and Alternative Therapies for Comorbid Sleep Disorders in Epilepsy.Current neuropharmacology · 2021Review
- Psychological treatments for people with epilepsy.The Cochrane database of systematic reviews · 2020Review
- Efficacy of internet-delivered cognitive behavioural therapy following an acute coronary event: A randomized controlled trial.Internet interventions · 2020Article
- Internet-delivered psychological treatments: from innovation to implementation.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2019Article
- Mobile Software as a Medical Device (SaMD) for the Treatment of Epilepsy: Development of Digital Therapeutics Comprising Behavioral and Music-Based Interventions for Neurological Disorders.Frontiers in human neuroscience · 2018Article
- DIY CBT for Comorbidities in Epilepsy.Epilepsy currentsArticle
- Feasibility and Acceptability of a Novel Online Program for Mental Health Carers.International journal of psychological researchArticle
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAnxiety and depression are highly prevalent in people with epilepsy (PWE) and contribute to increased disability. Unfortunately, there are numerous barriers (e.g., cost, distance, and stigma) and service gaps (e.g., lack of services and trained clinicians) that prevent many PWE from accessing traditional face-to-face psychological services. The aim of the present study was to examine the feasibility of a new transdiagnostic Internet-delivered cognitive behavioral therapy (iCBT) program, the Chronic Conditions Course, to simultaneously treat symptoms of anxiety, depression, and disability.
methodsA single-group feasibility open trial was employed involving 27 adults with epilepsy. The program comprises five online lessons delivered over 8 weeks and is provided with weekly contact from a mental health professional via e-mail and telephone.
resultsHigh treatment completion rates and levels of satisfaction were reported. Evidence of significant improvements in our primary outcomes (within-group Cohen's d [d]; average [avg.] reductions) of anxiety (d ≥ 1.28; avg. reduction ≥ 54%), depression (d ≥ 1.24; avg. reduction ≥ 54%), epilepsy-specific depression (d ≥ 0.95; avg. reduction ≥ 35%), and disability (d ≥ 0.62; avg. reduction ≥ 33%) were observed at posttreatment, which were sustained at or further improved to 3-month follow-up. On our secondary outcomes there were significant improvements for life satisfaction (d ≥ 0.70; avg. improvement ≥ 26%) but not for perceived cognitive difficulties (d ≥ 0.48; avg. reduction ≥ 15%). Highlighting the potential of the approach, relatively little clinician time was required per participant (mean 80.62 min, standard deviation [SD] 54.78), and the trial involved a broad range of geographically dispersed patients. SIGNIFICANCE: The findings of the current study support the feasibility and potential of transdiagnostic Internet-delivered treatments for adults with epilepsy. Further large-scale controlled trials are warranted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.