ArticleBrain imaging and behavior2017
Mapping temporo-parietal and temporo-occipital cortico-cortical connections of the human middle longitudinal fascicle in subject-specific, probabilistic, and stereotaxic Talairach spaces.
Article in Brain imaging and behavior, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.
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- Object-oriented hand dexterity and grasping abilities, from the animal quarters to the neurosurgical OR: a systematic review of the underlying neural correlates in non-human, human primate and recent findings in awake brain surgery.Frontiers in integrative neuroscience · 2024Pooled it
- Altered white matter integrity in pediatric bipolar disorder and the potential role of psychotic symptoms revealed by free water elimination corrected and superficial white matter DTI analyses.European child & adolescent psychiatry · 2026Article
- A Diagnosis Model of Typhoon-Related Post-Traumatic Stress Disorder Based on Fixel-Based Analysis in Machine Learning.Brain and behavior · 2026Article
- Mapping the Cross-species Brain Connectivity Atlas and Hemispheric Asymmetry of the Temporal Pole in Humans and Macaques.Neuroscience bulletin · 2026Article
- Inferior and Middle Longitudinal Fasciculus and Fornix Support Allocentric Representation.Hippocampus · 2025Article
- Hubs and interaction: the brain's meta-loop.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Networks for proper versus common name retrieval: insights from causal mapping and new hypotheses.Brain communications · 2025Review
- Math skills and microstructure of the middle longitudinal fasciculus: A developmental investigation.PloS one · 2025Article
- Neural correlates of musical timbre: an ALE meta-analysis of neuroimaging data.Frontiers in neuroscience · 2024Article
- Alterations in electroencephalographic functional connectivity in individuals with major depressive disorder: a resting-state electroencephalogram study.Frontiers in neuroscience · 2024Article
- Parcellating the vertical associative fiber network of the temporoparietal area: Evidence from focused anatomic fiber dissections.Brain & spine · 2024Article
- Supramarginal Gyrus and Angular Gyrus Subcortical Connections: A Microanatomical and Tractographic Study for Neurosurgeons.Brain sciences · 2023Article
- Stereotaxic cutting ofFrontiers in neuroanatomy · 2023Article
- A narrative review of the anatomy and function of the white matter tracts in language production and comprehension.Frontiers in human neuroscience · 2023Review
- A Proposed Human Structural Brain Connectivity Matrix in the Center for Morphometric Analysis Harvard-Oxford Atlas Framework: A Historical Perspective and Future Direction for Enhancing the Precision of Human Structural Connectivity with a Novel Neuroanatomical Typology.Developmental neuroscience · 2023Article
- Differences of resting fMRI and cognitive function between drug-naïve bipolar disorder and schizophrenia.BMC psychiatry · 2022Article
- An atlas of white matter anatomy, its variability, and reproducibility based on constrained spherical deconvolution of diffusion MRI.NeuroImage · 2022Article
- Converting sounds to meaning with ventral semantic language networks: integration of interdisciplinary data on brain connectivity, direct electrical stimulation and clinical disconnection syndromes.Brain structure & function · 2022Review
- Development of white matter tracts between and within the dorsal and ventral streams.Brain structure & function · 2022Article
Corrections and comments
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Authors and funding
13 authors at 7 institutions in 2 countries.
Funding
Abstract
Originally, the middle longitudinal fascicle (MdLF) was defined as a long association fiber tract connecting the superior temporal gyrus and temporal pole with the angular gyrus. More recently its description has been expanded to include all long postrolandic cortico-cortical association connections of the superior temporal gyrus and dorsal temporal pole with the parietal and occipital lobes. Despite its location and size, which makes MdLF one of the most prominent cerebral association fiber tracts, its discovery in humans is recent. Given the absence of a gold standard in humans for this fiber tract, its precise and complete connectivity remains to be determined with certainty. In this study using high angular resolution diffusion MRI (HARDI), we delineated for the first time, six major fiber connections of the human MdLF, four of which are temporo-parietal and two temporo-occipital, by examining morphology, topography, cortical connections, biophysical measures, volume and length in seventy brains. Considering the cortical affiliations of the different connections of MdLF we suggested that this fiber tract may be related to language, attention and integrative higher level visual and auditory processing associated functions. Furthermore, given the extensive connectivity provided to superior temporal gyrus and temporal pole with the parietal and occipital lobes, MdLF may be involved in several neurological and psychiatric conditions such as primary progressive aphasia and other aphasic syndromes, some forms of behavioral variant of frontotemporal dementia, atypical forms of Alzheimer's disease, corticobasal degeneration, schizophrenia as well as attention-deficit/hyperactivity Disorder and neglect disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.