Evidence map›Paper›PMID 27713802›Full record

ReviewCanadian Urological Association journal = Journal de l'Association des urologues du Canada

The role of voiding cystourethrography in the investigation of children with urinary tract infections.

Linda C Lee, Armando J Lorenzo, Martin A Koyle

Registry-linked trialOpen access · diamondAbstract readReview
In one paragraph

Review in Canadian Urological Association journal = Journal de l'Association des urologues du Canada. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03959163 (The Validity of the Quick Renal MRI in Pediatric Kidney Disease), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03959163 narecruitingnot on this map

The Validity of the Quick Renal MRI in Pediatric Kidney Disease

TypeinterventionalSponsorUniversity of Wisconsin, MadisonRan2019 to 2025Enrolled100ConditionsPyelonephritis, Pyelonephritis Acute, Renal SclerosisArmsQuick MRI
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Neurogenic Bladder in Children with Myelomeningocele.Diseases (Basel, Switzerland) · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Linda C LeeThe Hospital for Sick Children, Toronto, ON, Canada.
Armando J LorenzoThe Hospital for Sick Children, Toronto, ON, Canada;; Division of Urology, Department of Surgery, University of Toronto, Toronto, ON, Canada.
Martin A KoyleThe Hospital for Sick Children, Toronto, ON, Canada;; Division of Urology, Department of Surgery, University of Toronto, Toronto, ON, Canada.
Hospital for Sick Children · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urinary tract infections (UTIs) represent a common bacterial cause of febrile illness in children. Of children presenting with a febrile UTI, 25-40% are found to have vesicoureteral reflux (VUR). Historically, the concern regarding VUR was that it could lead to recurrent pyelonephritis, renal scarring, hypertension, and chronic kidney disease. As a result, many children underwent invasive surgical procedures to correct VUR. We now know that many cases of VUR are low-grade and have a high rate of spontaneous resolution. The roles of surveillance, antibiotic prophylaxis, endoscopic injection, and ureteral reimplantation surgery also continue to evolve. In turn, these factors have influenced the investigation of febrile UTIs. Voiding cystourethrography (VCUG) is the radiographic test of choice to diagnose VUR. Due to its invasive nature and questionable benefit in many cases, the American Academy of Pediatrics (AAP) no longer recommends VCUG routinely after an initial febrile UTI. Nevertheless, these guidelines pre-date the landmark Randomized Intervention of Children with Vesicoureteral Reflux (RIVUR) trial and there continues to be controversy regarding the diagnosis and management of VUR. This paper discusses the current literature regarding radiographic testing in children with febrile UTIs and presents a practical risk-based approach for deciding when to obtain a VCUG.

Identifiers

PMID27713802
PMCPMC5045350
OpenAlexW2419762826

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.