ReviewThe journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG
Calprotectin: Clinical Applications in Pediatrics.
Review in The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Pooled it
- Calprotectin protectsmSystems · 2025Article
- Calprotectin-mediated survival ofmBio · 2025Article
- Serum Calprotectin in the Evaluation of Gastrointestinal Diseases: An Ace up Your Sleeve?Medicina (Kaunas, Lithuania) · 2024Review
- Secretory-IgA binding to intestinal microbiota attenuates inflammatory reactions as the intestinal barrier of preterm infants matures.Clinical and experimental immunology · 2023Article
- Fecal Calprotectin and Cow's Milk-Related-Symptoms Score in Children with Cow's Milk Protein Allergy.Pediatric gastroenterology, hepatology & nutrition · 2023Article
- Factors associated with anaemia among preschool- age children in underprivileged neighbourhoods in Antananarivo, Madagascar.BMC public health · 2022Article
- Fecal calprotectin levels in pediatric cow's milk protein allergy.Frontiers in pediatrics · 2022Article
- Current status of fecal calprotectin as a diagnostic or monitoring biomarker for cow's milk protein allergy in children: a scoping review.World journal of pediatrics : WJP · 2021Article
- Gastrointestinal manifestations and their relation to faecal calprotectin in children with autism.Przeglad gastroenterologiczny · 2021Article
- Normal fecal calprotectin levels in healthy children are higher than in adults and decrease with age.Paediatrics & child health · 2020Article
- A Case of a 15-Month-Old With Periorbital Edema and Severe Anemia.Pediatrics · 2020Article
- Article
- Colonization by B. infantis EVC001 modulates enteric inflammation in exclusively breastfed infants.Pediatric research · 2019Article
- Comparison of a rapid test and an automated method for faecal calprotectin measurement.Practical laboratory medicine · 2019Article
- Natural chemotherapeutic alternatives for controlling of haemonchosis in sheep.BMC veterinary research · 2019Article
- Implications of hepatic dysfunction in Kawasaki disease: Time-related changes in aspartate aminotransferase, alanine aminotransferase, total bilirubin, and C-reactive protein levels.Pediatric investigation · 2019Article
- Combinatorial Omics Analysis Reveals Perturbed Lysosomal Homeostasis in Collagen VII-deficient Keratinocytes.Molecular & cellular proteomics : MCP · 2018Article
- Effects of herbal nutraceuticals and/or zinc against Haemonchus contortus in lambs experimentally infected.BMC veterinary research · 2018Article
- Diagnostic Accuracy of Serum and Urine S100A8/A9 and Serum Amyloid A in Probable Acute Abdominal Pain at Emergency Department.Disease markers · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As seen over the past 20 years, calprotectin has evolved as a novel, non-invasive biomarker of gastrointestinal (GI) inflammation. We present this review of calprotectin in pediatrics. This article will focus on studies using calprotectin concentrations from different body fluids to monitor inflammation in different disease states and conditions. The ultimate goal of our group is to lay down a foundation as we consider using calprotectin prospectively as a marker of intestinal inflammation that could lead to further testing and possibly a marker of preparedness for feeding. We surveyed all published studies in English of calprotectin in neonates, infants, children, and adolescents through February 2014. We will discuss calprotectin's basic properties and analysis such as characteristics, identification, presence in body fluids, and maturational development. In addition, calprotectin's use in inflammatory diseases exploring both GI and non-GI conditions will be evaluated and compared with other serum markers presently available. Finally, a summary of our findings and discussion of future work that could be undertaken in order to render calprotectin as a more useful monitoring tool to the medical research community will complete the review.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.