ArticlePharmaceuticals (Basel, Switzerland)2010
Antifungal Properties of Chenopodium ambrosioides Essential Oil Against Candida Species.
Article in Pharmaceuticals (Basel, Switzerland), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Chemical Composition and Biological Activity of Essential Oil fromMolecules (Basel, Switzerland) · 2026Article
- Phytochemical screening, UPLC analysis, evaluation of synergistic antioxidant and antibacterial efficacy of three medicinal plants used in Kinshasa, D.R. Congo.Scientific reports · 2025Article
- Chemical Composition, Antioxidant and Antibacterial Activities and Acute Toxicity ofMolecules (Basel, Switzerland) · 2023Article
- Essential oils fromFrontiers in pharmacology · 2022Review
- Delineating the Biofilm Inhibition Mechanisms of Phenolic and Aldehydic Terpenes againstACS omega · 2019Article
- Anti-biofilm Action ofFrontiers in microbiology · 2019Article
- Clausena anisata and Dysphania ambrosioides essential oils: from ethno-medicine to modern uses as effective insecticides.Environmental science and pollution research international · 2018Article
- Article
- Seasonal Microbial Conditions of Locally Made Yoghurt (Shalom) Marketed in Some Regions of Cameroon.International journal of food science · 2017Article
- Biological activities of extracts from Chenopodium ambrosioides Lineu and Kielmeyera neglecta Saddi.Annals of clinical microbiology and antimicrobials · 2012Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The essential oil of the aerial part (leaves, flowers and stem) of Chenopodium ambrosioides was obtained by hydrodistillation and its chemical composition analyzed by GC and GC/MS, which permitted the identification of 14 components, representing 98.8% of the total oil. Major components were α-terpinene (51.3%), p-cymene (23.4%) and p-mentha-1,8-diène (15.3%). The antifungal properties of this essential oil were investigated in vitro by the well diffusion and broth microdilution methods. The in vitro antifungal activity was concentration dependent and minimum inhibitory concentration values varied from 0.25 to 2 mg/mL. The in vivo antifungal activity was evaluated on an induced vaginal candidiasis rat model. The in vivo activity of the oil on mice vaginal candidiasis was not dose-dependent. Indeed, all the three tested doses; 0.1%, 1% and 10% led to the recovery of mice from the induced infection after 12 days of treatment. The effect of the essential oil on C. albicans ATCC 1663 fatty acid profile was studied. This oil has a relatively important dose-dependent effect on the fatty acids profile.
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Registered trials
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