ReviewPharmaceuticals (Basel, Switzerland)2010
The Treatment of Melioidosis.
Review in Pharmaceuticals (Basel, Switzerland), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Efficacy and safety of co-trimoxazole in eradication phase of melioidosis; systematic review.Annals of clinical microbiology and antimicrobials · 2023Pooled it
- Melioidosis imported to Northern Germany: a case report series.Infection · 2026Article
- Assessment of CD200R Activation in Combination with Doxycycline in a Model of Melioidosis.Microbiology spectrum · 2023Article
- Endemic melioidosis in central Taiwan-A longitudinal case cohort study.Frontiers in medicine · 2023Article
- Effective Therapeutic Options for Melioidosis: Antibiotics versus Phage Therapy.Pathogens (Basel, Switzerland) · 2022Review
- A Rare Case of Burkholderia Osteomyelitis Affecting the Hip Joint in an Adult.Journal of orthopaedic case reports · 2022Article
- Critical approach to atypical spectrum of melioidosis: a case-series based literature review.BMJ case reports · 2022Article
- Case of misdiagnosed melioidosis from Hue city, Vietnam.Iranian journal of microbiology · 2022Article
- Melioidosis: clinical aspects.Clinical medicine (London, England) · 2022Article
- Characterization ofVeterinary world · 2020Article
- Adapting Microarray Gene Expression Signatures for Early Melioidosis Diagnosis.Journal of clinical microbiology · 2020Article
- Human Melioidosis.Clinical microbiology reviews · 2020Review
- Article
- A review of melioidosis cases imported into Europe.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019Review
- Melioidosis with a subdural collection - a case report.BMC infectious diseases · 2019Article
- The relationship between bacterial sources and genotype to the antimicrobial resistance pattern ofVeterinary world · 2018Article
- Burkholderia pseudomallei infection presenting with a lung abscess and osteomyelitis in an adult man: A case report.Medicine · 2018Article
- Melioidosis in Sri Lanka.Tropical medicine and infectious disease · 2018Article
- A case report of melioidosis complicated by infective sacroiliitis in Sri Lanka.Tropical diseases, travel medicine and vaccines · 2018Article
- Host gene expression analysis in Sri Lankan melioidosis patients.PLoS neglected tropical diseases · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Melioidosis is a complex bacterial infection, treatment of which combines the urgency of treating rapidly fatal Gram negative septicaemia with the need for eradication of long-term persistent disease in pulmonary, soft tissue, skeletal and other organ systems. Incremental improvements in treatment have been made as a result of multicentre collaboration across the main endemic region of Southeast Asia and northern Australia. There is an emerging consensus on the three main patterns of antimicrobial chemotherapy; initial (Phase 1) treatment, subsequent eradication (Phase 2) therapy and most recently post-exposure (Phase 0) prophylaxis. The combination of agents used, duration of therapy and need for adjunct modalities depends on the type, severity and antimicrobial susceptibility of infection. New antibiotic and adjunct therapies are at an investigational stage but on currently available data are unlikely to make a significant impact on this potentially fatal infection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.