Evidence map›Paper›PMID 27712766›Full record

ReviewImmunology and allergy clinics of North America2016

Eosinophils and Mast Cells in Aspirin-Exacerbated Respiratory Disease.

John W Steinke, Spencer C Payne, Larry Borish

Open access · greenAbstract readReview
In one paragraph

Review in Immunology and allergy clinics of North America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 32 citations in OpenAlex.

  1. Circulating mast cell progenitors correlate with reduced lung function in allergic asthma.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2019
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  4. Low Prostaglandin EJournal of clinical medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

John W SteinkeDepartment of Medicine, Asthma and Allergic Disease Center, Carter Center for Immunology Research, University of Virginia Health System, 409 Lane Rd, Charlottesville, VA 22908, USA.
Spencer C PayneDepartment of Medicine, University of Virginia Health System, 409 Lane Rd, Charlottesville, VA 22908, USA; Department of Otolaryngology - Head and Neck Surgery, University of Virginia Health System, 409 Lane Rd, Charlottesville, VA 22908, USA.
Larry BorishDepartment of Medicine, Asthma and Allergic Disease Center, Carter Center for Immunology Research, University of Virginia Health System, 409 Lane Rd, Charlottesville, VA 22908, USA; Department of Microbiology, Asthma and Allergic Disease Center, Carter Center for Immunology Research, University of Virginia Health System, 409 Lane Rd, Charlottesville, VA 22908, USA. Electronic address: lb4m@virginia.edu.
University of Virginia Health System · US

Funding

An Evaluation of Treatment with Omalizumab to Improve the Asthmatic Response to aU01AI100799 · NIAID · UNIVERSITY OF VIRGINIA · PI HEYMANN, PETER W, PLATTS-MILLS, THOMAS A. · 2012 to 2015
$5.3M
Interplay between LTE4/LTE4 receptors and IFN-y with mast cells and eosinophils iR01AI057438 · NIAID · UNIVERSITY OF VIRGINIA · PI BORISH, LARRY C · 2006 to 2015
$3.7M
Clinical response to rhinovirus challenge in human asthmaticsU01AI123337 · NIAID · UNIVERSITY OF VIRGINIA · PI BORISH, LARRY C · 2016 to 2020
$3.6M
Clinical immune response to rhinovirus challenge in human asthmaticsR56AI120055 · NIAID · UNIVERSITY OF VIRGINIA · PI BORISH, LARRY C · 2015 to 2015
$386k
NIAID NIH HHS R01 AI057438NIAID NIH HHS R56 AI120055NIAID NIH HHS U01 AI100799NIAID NIH HHS U01 AI123337
6 · The paper itself

Abstract

Aspirin-exacerbated respiratory disease (AERD) involves overexpression of proinflammatory mediators, including 5-lipoxygenase and leukotriene C

Indexed as

Anti-Inflammatory Agents, Non-SteroidalAspirinBiomarkersCytokinesEosinophilsGene Expression RegulationHumansInflammation MediatorsLeukocyte CountMast CellsRespiratory Tract DiseasesSignal TransductionAnti-Inflammatory Agents, Non-SteroidalAspirinBiomarkersCytokinesInflammation MediatorsArachidonic acidAspirin-exacerbated respiratory diseaseCyclooxygenaseEosinophilLeukotrieneMast cellProstaglandin

Identifiers

PMID27712766
PMCPMC5116300
OpenAlexW2518689799

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.